HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 1 of 167
If a drug is active against the preerythrocytic stage of the malarial parasite it will be useful as a
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Question 2 of 167
The drug of choice for Kala Azar is
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Question 3 of 167
A 24-year-old primigravid woman’s water breaks at 39 weeks gestation. Twenty-four hours later, she is having regular contractions 3 min apart. Her labor lasts 8 h. At the hospital, she gives birth to a baby boy, who initially appeared healthy. Within the next 12 h, the baby boy begins to have temperature fluctuations, difficulty breathing, and reduced movements. You suspect neonatal sepsis, so IV ampicillin is started. Which additional antibiotic could be given simultaneously to have a synergistic effect in controlling this infection?
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Question 4 of 167
A 73-year-old man with overwhelming sepsis requiring intravenous fluid support, pressors, and antibiotics is now beginning to improve clinically. The rationale against the use of a bacteriostatic antibiotic in this patient includes which of the following?
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Question 5 of 167
The following is true of quinine
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Question 6 of 167
Tumor necrosis factor - α - appears to play an important role in autoimmunity and inflammatory diseases. Which of the following is a humanized monoclonal antibody that binds to TNF - a and inhibits its action?
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Question 7 of 167
A 12-year-old male complains of red plaques covered by silver scales on his elbows and knees. He has one older sister with similar lesions. In each case, the lesions are worse in the winter months. His pediatrician prescribes acitretin. Which of the following may this boy experience as a result of this treatment?
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Question 8 of 167
A patient develops severe, watery diarrhea, fever & abdominal pain. Clostridium difficile infection in the gut is confirmed. The antimicrobial therapy for this antibiotic-associated pseudomembranous colitis is:
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Question 9 of 167
Body surface area (BSA) is used in calculating chemotherapy doses because
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Question 10 of 167
Clostridium difficile infection is treated by which of the following:
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Question 11 of 167
Over 90% of this drug is excreted in the urine in intact form. Because its urinary solubility is low, patients should be well hydrated to prevent nephrotoxicity
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Question 12 of 167
A 39-year-old man with aortic insufficiency and a history of multiple antibiotic resistances is given a prophylactic intravenous dose of antibiotic before surgery to insert a prosthetic heart valve. As the antibiotic is being infused, the patient becomes flushed over most of his body. Which of the following antibiotics is most likely responsible?
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Question 13 of 167
Third generation cephalosporins has the following characteristic EXCEPT:
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Question 14 of 167
The following is Wrong concerning selective estrogen receptor modulators:
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Question 15 of 167
Six years ago, a woman experienced an episode of bronchospasm following penicillin V therapy. Now she has an upper respiratory infection. Her sputum culture reveal a strain of streptococcus pneumoniae that is sensitive to the following drugs: Which of these drugs would be the best choice of this patient?
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Question 16 of 167
An example of a cytokine is
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Question 17 of 167
The primary reason for the use of drug combinations in the treatment of tuberculosis is to
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Question 18 of 167
This drug has been used prophylactically in contacts of children with infection due to Haemophilus influenzae type B. It is also prophylactic in meningococcal and staphylococcal carrier states. While the drug eliminates a majority of meningococci from carriers, highly resistant strains may be selected out during treatment
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Question 19 of 167
Which of the following herbs should be used with caution while driving or performing other tasks that require alertness and coordination?
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Question 20 of 167
The main side effect of chloramphenicol is:
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Question 21 of 167
Which of the following drugs is an antimetabolite that inhibits a trypanosomal enzyme involved in putrescine synthesis?
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Question 22 of 167
A 63-year-old woman presents with a productive cough, shortness of breath, and fever and chills. Past medical history is significant for chronic renal disease. After a standard dose of which of the following drugs would you expect to see the greatest increase in serum drug concentration?
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Question 23 of 167
The drug of choice for vaginal trichomoniasis in a non-pregnant woman is:
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Question 24 of 167
A 39-year-old female is scheduled to undergo a laparoscopic cholecystectomy. Induction of anesthesia will be undertaken with fospropofol instead of propofol. Advantages of fospropofol over propofol include which of the following?
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Question 25 of 167
Patients taking this drug might be advised to test their vision by reading the small print in the newspaper from time to time. This drug is
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Question 26 of 167
Yellow pigmentation of the skin is most common with
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Question 27 of 167
The following is (are) used in acromegaly and in Parkinsonism:
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Question 28 of 167
Which of the following drugs is a tetracycline antibiotic:
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Question 29 of 167
The False statement concerning co-trimoxazole is:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 30 of 167
Which of the following chemotherapy agents acts by intercalation?
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Question 31 of 167
A 28-year-old man presents to the emergency department with diarrhea for the past 2 days. He went on a camping trip 10 days ago. His loose stools are foul smelling and have been associated with abdominal pain and nausea. Stool analysis shows cysts. What is the most appropriate treatment?
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Question 32 of 167
The drug, inhibiting uncoating of the viral RNA:
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Question 33 of 167
Which of the following antimalarial drugs is more active against pre-and exoerythrocytic stages of the malarial parasite than against the erythrocytic stage?
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Question 34 of 167
Which of the following drugs is used for candidiasis treatment:
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Question 35 of 167
Azoles have an antifungal effect because of:
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Question 36 of 167
The principal active alkaloid of ipecac is
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Question 37 of 167
Chemical interactions between this drug and cell membrane components can result in the formation of pores lined by hydrophilic groups present in the drug molecule.
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Question 38 of 167
Each of the following antibacterial agents is paired with an appropriate mechanism of action EXCEPT:
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Question 39 of 167
A 10 year old boy with glucose-6-phosphate dehydrogenase deficiency has typhoid fever, the best drug for treatment is:
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Question 40 of 167
A 5-year-old male patient’s parents complain of recurring fever in their son over the course of a month. Past medical history is significant for easy bruisability. A CBC reveals a white blood cell count of 30,000 cells per microliter. A bone marrow biopsy confirms the diagnosis of acute lymphoblastic leukemia. This child is started on a chemotherapeutic regimen. Which of the following chemotherapy drugs interferes with DNA synthesis after its metabolite is incorporated into the growing DNA strand?
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Question 41 of 167
Prednisolone
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Question 42 of 167
The following is WRONG concerning leuprolide & nafarelin:
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Question 43 of 167
All the following drugs have cross sensitivity with penicillin, EXCEPT:
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Question 44 of 167
A 33-year-old sexually active female with a history of recurrent vulvar Candida infections presents to her primary care physician for guidance. She has tried treatment with topical miconazole and also with nystatin powder. What is the likely clinical outcome given that she has been treated with both agents?
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Question 45 of 167
Multidrug therapy with dapsone, rifampin and clofazimine is the treatment of choice of
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Question 46 of 167
Augmentin has the following specifications EXCEPT:
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Question 47 of 167
Azathiprone
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Question 48 of 167
Which of the following is true of acyclovir treatment of genital herpes simplex?
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Question 49 of 167
Which of the following is not an anti-fungal drug:
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Question 50 of 167
A 17-year-old high school football player presents to clinic with painful burning of his feet. Football practice started 3 weeks ago, and for the past week, he has had blisters and cracking of the skin of his feet. The skin between his toes is erythematous and scaly. He is diagnosed with tinea pedis and started on clotrimazole. What is the mechanism of action of clotrimazole?
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Question 51 of 167
Which of the following compounds is a good substrate for hypoxanthine-guanine phosphoribosyltransferase in trypanosomes (but not mammals) and is eventually converted into metabolites that are incorporated into RNA?
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Question 52 of 167
A 23-year-old woman presents to her primary care physician with dysuria and urgency. Urine is positive for leukocyte esterase and nitrites. Her physician prescribes co-trimoxazole for her UTI. How does co-trimoxazole inhibit bacterial growth?
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Question 53 of 167
A 71-year-old man with osteomyelitis is treated with aminoglycosides. Blood cultures are drawn and reveal resistance to this antibiotic class. What is the most likely reason for this to occur?
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Question 54 of 167
A 4-year-old boy is hospitalized on the pediatric service with cough, runny nose, and chest pressure. Concern for respiratory syncytial virus is brought up by the treating physician. Treatment with zanamivir is undertaken. Which of the following underlying conditions can worsen bronchospasm in this patient?
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Question 55 of 167
Montelukast is:
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Question 56 of 167
The following is used in acromegaly & in hyperprolactinemia:
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Question 57 of 167
Grey baby syndrome is a reported complication of:
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Question 58 of 167
A 35-year-old female patient has just received a bone marrow transplant and is taking immunosuppressants. Two days after starting her immunosuppression regimen, she develops dyspnea, chest pain, and hemoptysis. A galactomannan test confirms a diagnosis of aspergillosis. She is given multiple drugs to combat this new infection, one of which is caspofungin. How does caspofungin work?
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Question 59 of 167
Minocycline hydrochloride is a member of which class of anti-infective agents:
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Question 60 of 167
Albendazole is less effective than mebendazole in the following helminthic infestation
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Question 61 of 167
A 35-year-old woman complains of itching in the vulval area. Hanging-drop examination of the urine reveals trichomonas. Which of the following is the preferred treatment for the trichomoniasis?
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Question 62 of 167
A 37-year-old man with a schizophrenia presents to the emergency room with worsening symptoms. He has been hearing voices in his head that tell him to hurt other people. He is scared by these thoughts and wants help. He is currently taking risperidone. The physician changes him to clozapine. What should the physician monitor while the patient is taking clozapine?
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Question 63 of 167
Gamma immunoglobulin is considered
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Question 64 of 167
A 43-year-old man with leukemia is hospitalized for treatment after his prior chemotherapeutic regimen failed to produce remission. Bone marrow biopsy is repeated and indicates the presence of hairy cell leukemia. Treatment with fludarabine has begun. This agent likely works in which of the following ways?
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Question 65 of 167
Disturbance of vitamin K-dependent clotting function is associated with:
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Question 66 of 167
The drug of choice in patients allergic to penicillin is:
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Question 67 of 167
The best product to treat vulvar pruritus in a woman with a vaginal yeast infection is
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Question 68 of 167
Which of the following is not a first line antitubercular drug?
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Question 69 of 167
The drug used in severe intestinal or hepatic amebiasis is:
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Question 70 of 167
The following are aminoglycoside antibiotics EXCEPT:
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Question 71 of 167
Regarding imipenem, which of the following is INCORRECT?
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Question 72 of 167
Which one of the following statements about the mechanisms of action of drugs used in cancer chemotherapy is least accurate?
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Question 73 of 167
Hematological studies are most likely to show a low reticulocyte count in a patient who has which one of the following abnormalities?
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Question 74 of 167
Which of the following is an advantage of benzyl penicillin use:
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Question 75 of 167
A 26-year-old female with a 2-week history of urinary urgency and frequency presents to her primary care physician for evaluation. Urinalysis reveals nitrates, leukocytes, and red blood cells. The physician selects a quinolone antibiotic for treatment of a presumed urinary tract infection. Which of the following organisms would be most sensitive at the lowest drug concentration?
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Question 76 of 167
Which one of the following statements about flucytosine is accurate?
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Question 77 of 167
Twenty months after finishing her chemotherapy, the woman had a relapse of breast cancer. The cancer was now unresponsive to standard doses of chemotherapy. The decision was made to treat the patient with high-dose chemotherapy followed by autologous stem cell transplantation. Which of the following drugs is most likely to be used to mobilize the peripheral blood stem cells for the patient's autologous stem cell transplantation?
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Question 78 of 167
A young woman employed as a dental laboratory technician complains of conjunctivitis, skin irritation, and hair loss. On examination, she has perforation of the nasal septum and a 'milk and roses' complexion. These signs and symptoms are most likely to be due to
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Question 79 of 167
Cyclosporine is used for:
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Question 80 of 167
The preferred drug for controlling an acute exacerbation of ulcerative colitis is
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Question 81 of 167
A 24-year-old man complains of night sweats, weight loss, and pruritus over several weeks. Physical exam shows nontender lymphadenopathy. A lymph node biopsy reveals Reed-Sternberg cells. He is started on a chemotherapy regimen including one drug that works primarily by trapping cells in the mitotic (M) phase of the cell cycle. Which drug is this?
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Question 82 of 167
Which one of the following anticancer drugs acts in the M-phase of the cell cycle to prevent disassembly of the mitotic spindle?
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Question 83 of 167
A 34-year-old male patient with HIV disease presents to the walk-in clinic of the emergency department with pain and blurry vision in his right eye. A dilated ophthalmoscopic exam of the right eye reveals a diffuse retinitis. What is the most appropriate treatment for this patient?
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Question 84 of 167
Plasmodial resistance to chloroquine is due to
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Question 85 of 167
Ethylenediamine-tetracetic acid is an antidote for which of the following?
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Question 86 of 167
A 35-year-old man with HIV disease presents to the emergency department with a severe headache and fever for the past 6 h. His fever was measured to be 103°F. He also has chills, stiff neck, and nausea. He is diagnosed with Cryptococcus neoformans meningitis and started on amphotericin B. What is the mechanism of action of amphotericin B?
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Question 87 of 167
Which of the following is a polysaccharide used for active immunization in patients with chronic cardiorespiratory ailments?
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Question 88 of 167
A 58-year-old woman presents to the ambulatory care clinic with repetitive, uncontrollable lip smacking and puckering. Past medical history includes Type-2 diabetes for which she takes glipizide and metformin, hypercholesterolemia for which she takes lovastatin, bipolar disorder for which she takes haloperidol, and hypertension for which she takes hydrochlorothiazide. Which of her medications is likely causing her symptoms?
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Question 89 of 167
Fexofenadine is a metabolite of:
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Question 90 of 167
Tinidazole differs from metronidazole in that
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Question 91 of 167
An inhibitor of nucleic acid synthesis useful against anerobes:
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Question 92 of 167
Antifungal drugs as amphotericin B has the following EXCEPT:
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Question 93 of 167
A 34-year-old man with a history of recurrent tuberculosis on a multidrug regimen, including isoniazid. He presents to his primary care physician complaining of paresthesias of his hands and feet. What is the most likely explanation for this finding?
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Question 94 of 167
Erythrocytic schizontocide antimalarial drugs are used as
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Question 95 of 167
All of the following drugs demonstrate a fungicidal effect, EXCEPT:
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Question 96 of 167
Antiretroviral therapy is not recommended in asymptomatic HIV infected subjects because of the following reason(s).
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Question 97 of 167
Chloroquine acts as
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Question 98 of 167
Which one of the following antiseptics promotes wound healing?
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Question 99 of 167
A 64-year-old man who has a history of transient ischemic attacks is taking clopidogrel. He presents to his primary care physician for follow-up. Which of the following should the primary care physician be concerned about in this patient?
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Question 100 of 167
The following is true concerning oral contraceptives:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 101 of 167
An 18-year-old female plans to take a mission trip to Ghana for 2 weeks during the summer following her senior year of high school. Her doctor recommends starting a regimen of mefloquine before her trip for malaria prophylaxis rather than the traditional chloroquine because of widespread resistance to chloroquine. What is the mechanism of chloroquine resistance?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 102 of 167
A 52-year-old man with recurrent Pseudomonas infections now has another infection. Culture and sensitivity now indicate that this pathogen is not sensitive to chloramphenicol. What is the most likely reason for development of resistance?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 103 of 167
When does not neutrophil nadir associated with chemotherapy agents generally occur?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 104 of 167
Stimulation of H-receptors can produce the following effects, choose the false one:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 105 of 167
An important therapeutic or toxic effect of loop diuretics is
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 106 of 167
Which of the following statements regarding signal transduction is incorrect?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 107 of 167
Choose the correct statement(s) about metronidazole
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 108 of 167
A 52-year-old female presents with facial wrinkling that has not been satisfactorily treated with creams. She requests information on botulinum toxin A at an acquaintance’s recommendation. Botulinum toxin’s mechanism of action is most similar to which other bacterial toxin?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 109 of 167
A 45-year-old man with HIV disease and herpesvirus has begun on therapy with foscarnet. The medication is administered intravenously. If serum electrolytes are drawn on this patient after 1 week of therapy, which of the following laboratory values would be expected to be abnormal?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 110 of 167
Chemoprophylaxis for travelers to geographic regions where chloroquine-resistant P falciparum is endemic is best provided by
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 111 of 167
Which of the following is contraindicated in the presence of active tuberculosis?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 112 of 167
Which one of the following drugs is recommended as a single agent for oral treatment of uncomplicated malaria due to chloroquine-resistant P falciparum strains?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 113 of 167
Reduction in calcium absorption from GIT is associated with the use of:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 114 of 167
A jaundiced 1-day-old premature infant with elevated free bilirubin is seen in the premature baby nursery. The mother had received an antibiotic combination for a urinary tract infection (UTI) 1 week before delivery. Which of the following is the most likely cause of the baby's kernicterus?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 115 of 167
Which is NOT an advantage of dalteparin over unfractionated heparin?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 116 of 167
This drug is the preferred agent for teatment of nocardiosis and, in combination with pyrimethamine, is prophylactic against preumocystis carinii infections in AIDS patiens.
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 117 of 167
A 26-year-old sexually active man presents to his primary care physician with a nonpruritic maculopapular rash on his palms. He reports that about 6 weeks ago, he developed a nonpainful ulcer on his penis that healed spontaneously. Benzathine penicillin G is administered. Twelve hours later, he begins to have myalgia, fever, and chills. What is the most likely cause of this new onset of symptoms?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 118 of 167
When comparing the effects of overdose of meperidine and morphine in the emergency department evaluation of patients, which of the following features would be characteristic of meperidine overdose?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 119 of 167
A 55-year-old executive has cardiomyopathy and congestive heart failure. He is being treated with diuretics. The mechanism of action of furosemide is best described as
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 120 of 167
The only antifungal drug which has some activity against moulds like Mucor and Aspergillus is
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 121 of 167
All of the following agents have been used in drug regimens for the treatment of breast carcinoma. Which one has specific activity in a subset of female breast cancers?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 122 of 167
Select the sulfonamide drug which is active against pseudomonas and is used by topical application for prophylaxis of infection in burn cases
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 123 of 167
Griseofulvin is indicated in.
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 124 of 167
Trimethoprim is combined with sulfamethoxazole in a ration of 1:5 to yield a steady state plasma concentration ratio of
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 125 of 167
Which of the following drugs is most likely to cause additive anemia and neutropenia if administered to an AIDS patient taking zidovudine?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 126 of 167
A patient on antibacterial therapy has to do an operation in which a skeletal muscle relaxant may be used. He will be at risk if this antimicrobial is:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 127 of 167
Which one of the following drugs is most likely to be effective in the treatment of gonorrhea in this patient and safe to use?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 128 of 167
Concerning argatroban (direct thrombin inhibitor), the following is Wrong:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 129 of 167
A 21-year-old woman college student presents to an urgent care clinic with vaginal discharge for the past 3 days. The whitish discharge has a foul odor. A wet prep of the discharge shows squamous cells surrounded by rod-shaped bacteria. The addition of KOH produces a positive whiff test. What is the most appropriate for this patient?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 130 of 167
A 66-year-old man with a history of gout was recently diagnosed with non-Hodgkin’s lymphoma. Because of frequent gout attacks, he has been placed on allopurinol. He is started on medication for his lymphoma, and shortly after, he develops GI upset and elevated liver enzymes. Because of taking allopurinol, what medication should have been avoided in this patient?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 131 of 167
The penicillin G preparation with the longest duration of action is:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 132 of 167
Choose the correct statement about mefloquine
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 133 of 167
Isoniazid has following unwanted effect:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 134 of 167
Hypersensitivity reaction is a common and serious complication to:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 135 of 167
A 22-year-old sexually active man presents to the ambulatory care clinic with dysuria, penile discharge, and a swollen right knee. A joint aspirate of his right knee reveals many neutrophils as well as some gram-negative diplococci. Which is the best choice to treat his condition?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 136 of 167
Antimicrobial treatment does not alter the course of the following diarrhoeas except
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 137 of 167
Infections due to gram-negative bacilli have occurred when this agent has been used as a skin antiseptic
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 138 of 167
Select the drug used in the treatment of filariasis
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 139 of 167
The following 5-HT antagonist has an antihypertensive effect:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 140 of 167
Mycobat tuberculosis infection in a HI V infected patient is treated with
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 141 of 167
An 8-year-old boy presents to the clinic with an extremely itchy rash for the past 2 days. He is the fourth student from his class to present with the same symptoms. The rash is across his hands, wrists, and elbows bilaterally. Small erythematous papules with obvious burrows, which look like insect bites, are aligned in 8-cm segments. What is the most appropriate treatment?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 142 of 167
A 25-year-old G1P0 woman presents to the emergency department with shaking chills, chest pain, and productive cough. A chest X-ray reveals an area of opacity in the right lower lobe. The physician's choice of antibiotics is limited because some may harm this patient's fetus. Which of the following antibiotics may cause hearing loss in her fetus?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 143 of 167
Nalidixic acid is primarily active against
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 144 of 167
Metronidazole is NOT useful in the treatment of:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 145 of 167
Passive immunization involves
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 146 of 167
The following is NOT an advantage of rivaroxiban and dabigatran over warfarin:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 147 of 167
According to the currect WHO guidelines new (untreated) sputum smear positive cases of pulmonary tuberculosis are to be treated with the following regimen
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 148 of 167
The following antiamoebic drug should not be used in children because of risk of causing blindness
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 149 of 167
Ofloxacin is classified as a (an):
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 150 of 167
The drug used for influenza A prevention is:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 151 of 167
Metronidazole is effective in all of the following EXCEPT:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 152 of 167
Cefoperazone is associated with a high risk of:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 153 of 167
An 18-year-old male college student presents to the emergency room with a fever of 103°F and stiff neck for the past 3 h. After a lumbar puncture and Gram stain, the diagnosis of meningococcal meningitis is established. Unfortunately, his college did not require students to have the meningococcal vaccine. What prophylaxis should be given to his close contacts in the dorm?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 154 of 167
A 47-year-old woman with a rheumatoid arthritis comes to clinic for her annual visit. Her arthritis has not worsened over the past 6 months since starting on infliximab. Her arthritis is worst in the joints of her hands. After her morning stiffness ceases, she can usually go through the rest of the day with minimal pain. What is the mechanism of action of infliximab?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 155 of 167
Which one of the following antiviral drugs is effective against hepatitis B and C infections:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 156 of 167
Clarithromycin is classified as:
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 157 of 167
Which of the following is not correctly matched to mechanism of action?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 158 of 167
An 8-month-old female infant is brought to the emergency department by her parents. She is febrile, tachycardic, and hypotensive. Sepsis is suspected and the physician wants to give chloramphenicol but is worried about gray baby syndrome. Why does chloramphenicol sometimes cause gray baby syndrome in infants?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 159 of 167
A 46-year-old woman with chronic pelvic pain caused by endometriosis consults a pain management specialist regarding options for treatment. Which of the following statements is true regarding chronic pain management in this patient?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 160 of 167
A 22-year-old African American man who is a college student plans to travel to Africa for a semester of study abroad. A university student health physician prescribes chloroquine for malaria prophylaxis starting 2 weeks before the trip. Soon after starting the regimen, the patient develops scleral icterus. What is the most likely underlying cause for the icterus?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 161 of 167
A man with a history of multiple antibiotic resistance is given a prophylactic IV dose of antibiotic before surgery. As the antibiotic is being infused, the patient becomes flushed over most of his body. Which of the following antibiotics is most likely responsible?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 162 of 167
Which of the following is the most effective agent in the treatment of Rickettsia, Mycoplasma, and Chlamydia infections?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 163 of 167
A 31-year-old man has gonorrhea. He has no drug allergies, but he recalls that a few years ago while in Africa he had acute hemolysis following use of an antimalarial drug. The physician is concerned that the patient has an accompanying urethritis due to C trachomatis, though no cultures or enzyme tests have been performed. Which of the following drugs is most likely to be effective against gonococci and to eradicate C trachomatis in this patient?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 164 of 167
A 21-year-old female presented to clinic for lesions on her vulva. The painful and itchy lesions have a red base and are vesicular. She recently has had a new sexual partner. The diagnosis of herpes is established and the patient is started on acyclovir. She becomes resistant to acyclovir and it therefore becomes ineffective. What is the mechanism of resistance for acyclovir?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 165 of 167
A 19-year-old college student man presents to the student health service with a 2-week history of headache, malaise, sore throat, and dry cough, which has become productive over the last 4 days. He states that several of his dorm mates have complained of similar problems in the last few weeks. Pulmonary auscultation reveals scattered coarse rhonchi bilaterally. What is the best treatment for this patient?
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 166 of 167
The most important reason for using a combination of chemotherapeutic agents in the treatment of tuberculosis is
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HESI LPN · HESI NCLEX questions on chemotherapy drugs
Question 167 of 167
The following anthelmintic has been found to be safe during pregnancy
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