HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 1 of 52
The client is taking IV heparin. The nurse will want to look out for what adverse reaction of the drug?
A
Pulmonary embolism
B
Deep vein thrombosis
C
Thrombocytopenia
D
Neutropenia
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 2 of 52
The client has a heart rate of 40 with electrical activity beginning at the AV node. What type of rhythm is the client having?
A
Normal sinus rhythm
B
Atrial flutter
C
Atrial fibrillation
D
Junctional escape rhythm
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 3 of 52
Which of the following NSAIDs is an indol derivative?
A
Ibuprofen
B
Indomethacin
C
Meclofenamic acid
D
Diclofenac
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 4 of 52
A client has been severely depressed and suicidal. After admission to an inpatient psychiatric unit, antidepressant medication is administered. As the client becomes more energized and communicative, what should be the priority nursing intervention for this client?
A
Allowing the client to have unsupervised passes to his or her home
B
Encouraging the client to participate in group activities
C
Increasing the vigilance regarding the client's suicidal precautions
D
Recognizing that the client's suicidal potential has decreased
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 5 of 52
Sulfonamide potency is decreased in case of co-administration with:
A
Oral hypoglycemic agents
B
Local anesthetics – derivatives of paraaminobenzoic acid
C
Local anesthetics – derivatives of benzoic acid
D
Non-narcotic analgesics
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 6 of 52
This drug is contraindicated in patients with bronchial asthma:
A
Propranolol
B
Clonidine
C
Enalapril
D
Nifedipine
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 7 of 52
All statements are true EXCEPT: Doxazosin:
A
Is a selective reversible alpha_1 receptor antagonist
B
Should always be prescribed with a beta blocker to prevent reflex tachycardia
C
Is associated with first-dose hypotension
D
Reduces plasma LDL/high-density lipoprotein (HDL) cholesterol ratio
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 8 of 52
Which of the following antipsychotic drugs has the high risk of potentially fatal agranulocytosis and risk of seizures at high doses?
A
Haloperidol
B
Risperidone
C
Clozapine
D
Chlorpromazine
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 9 of 52
Which of the following agents is an alfa2-selective agonist with ability to promote constriction of the nasal mucosa?
A
Xylometazoline
B
Phenylephrine
C
Methoxamine
D
Epinephrine
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 10 of 52
Actoprotectors are:
A
Stimulators,improving physical efficiency
B
Cognition enhancers improving the highest integrative brain function
C
Stimulants raising non-specific resistance towards stresses
D
Agents,stimulating the bulbar respiratory and vasomotor centers
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 11 of 52
Class of I.V. IgG preparation is:
A
Monoclonal antibodies
B
Immunosuppressive agents
C
Interferons
D
Immunoglobulins
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 12 of 52
A patient with depression tells the nurse, 'I don’t think I want to take that SSRI medication the doctor told me she would prescribe. I don’t understand what it will do.' Which of the following would be the most helpful response?
A
Medications help your brain; they don’t mess things up.'
B
The medication will correct a deficiency of one of the chemicals needed to maintain a normal mood.'
C
SSRIs are a new classification of drugs that are getting good results while having very few unpleasant side effects.'
D
What is it you are afraid of?'
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 13 of 52
The nurse notes in a patient’s medical record that nesiritide (Natrecor) has been ordered. Based on this order, the nurse interprets that the patient has which disorder?
A
Atrial fibrillation
B
Acutely decompensated heart failure with dyspnea at rest
C
Systolic heart failure
D
Long-term treatment of heart failure
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 14 of 52
The principal mechanism of fomepizol action is associated with inhibition of:
A
Aldehyde dehydrogenase
B
Acetylcholinesterase
C
Alcohol dehydrogenase
D
Monoamine oxidase
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 15 of 52
This drug is contraindicated in patients with moderate to severe heart failure:
A
Nifedipine
B
Verapamil
C
Both of the above
D
None of the above
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 16 of 52
Which of the following opioid receptor types is responsible for euphoria and respiratory depression?
A
Kappa-receptors
B
Delta-receptors
C
Mu-receptors
D
All of the above
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 17 of 52
General contraindications for anticancer drugs are:
A
Depression of bone marrow
B
Acute infections
C
Severe hepatic and/or renal insufficiency
D
All of the above
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 18 of 52
Which of the following hormones is produced by the anterior lobe of the pituitary?
A
Thyrotropin-releasing hormone (TRH)
B
Corticotropin-releasing hormone (CRH)
C
Growth hormone (somatotropin GH)
D
Growth hormone-releasing hormone (GHRH)
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 19 of 52
A 58-year-old man undergoes open heart surgery for a triple coronary artery bypass graft. His surgery goes smoothly, but the next day, he develops chest palpitations. Verapamil is started to keep his supraventricular tachycardia from interfering with ventricular rhythm. Under which Singh-Vaughan Williams class of antiarrhythmics does verapamil fall?
A
Class Ia
B
Class Ib
C
Class Ic
D
Class IV
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 20 of 52
When is it not possible to blind a clinical trial using a placebo control group?
A
in treatments where a convincing placebo treatment would be too dangerous to be ethically acceptable (e.g. surgery)
B
in treatments where the active participation of the patient is necessary (e.g. physical therapy)
C
in treatments where the standard placebo may have a deleterious effect on research participants (e.g. for diabetics)
D
A and B
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 21 of 52
When giving dextromethorphan, the nurse understands that this drug suppresses the cough reflex by which mechanism of action?
A
Causing depression of the central nervous system
B
Anesthetizing the stretch receptors
C
Having direct action on the cough center
D
Decreasing the viscosity of the bronchial secretions
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 22 of 52
Which of the following drugs is a class IV antiarrhythmic that is primarily indicated for the treatment of supraventricular tachyarrhythmias?
A
Lbutilide
B
Mexiletine
C
Diltiazem
D
Quinidine
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 23 of 52
Benzodiazepine′s usefulness is limited by:
A
Tolerance
B
Atropine-like symptoms
C
Psychotic episodes
D
Myasthenic syndrome
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 24 of 52
Route of administration of 25-hydroxyvitamin D3 (calcifediol) is:
A
Oral
B
Subcutaneous
C
Intravenous
D
Intranasal
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 25 of 52
The reasons determing bioavailability are:
A
Rheological parameters of blood
B
Amount of a substance obtained orally and quantity of intakes
C
Extent of absorption and hepatic first-pass effect
D
Glomerular filtration rate
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 26 of 52
Tick the luminal amebecide drug:
A
Metronidazole
B
Emetine
C
Doxycycline
D
Diloxanide
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 27 of 52
Rickets is:
A
A deficiency disease resulting from a lack of vitamin D or calcium and from insufficient exposure to sunlight, characterized by defective bone growth and occurring chiefly in children
B
A disease occurring primarily in adults that results from a deficiency in vitamin D or calcium and is characterized by a softening of the bones with accompanying pain and weakness
C
A disease characterized by a decrease in bone mass and density, occurring especially in postmenopausal women, resulting in a predisposition to fractures and bone deformities such as a vertebral collapse
D
All of the above
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 28 of 52
Which doses of Aspirin may be more effective in inhibiting Tromboxane A2?
A
Low
B
High
C
All of the Above
D
None of the above
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 29 of 52
Select the most appropriate hypolipidemic drug for a patient with raised LDL-cholesterol level but normal triglyceride level
A
A HMG - CoA reductase inhibitor
B
A fibric acid derivative
C
Probucol
D
Nicotinic acid
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 30 of 52
Bactericidal effect is:
A
Inhibition of bacterial cell division
B
Inhibition of young bacterial cell growth
C
Destroying of bacterial cells
D
Formation of bacterial L-form
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 31 of 52
The patient is receiving digoxin for treatment of heart failure. Which finding would suggest to the nurse that the heart failure is improving?
A
Pale and cool extremities
B
Absence of peripheral edema
C
Urine output of 60 mL every 4 hours
D
Complaints of increasing dyspnea
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 32 of 52
All of the following statements about efficacy and potency are true EXCEPT:
A
Efficacy is usually a more important clinical consideration than potency
B
Efficacy is the maximum effect of a drug
C
Potency is a comparative measure, refers to the different doses of two drugs that are needed to produce the same effect
D
The ED50 is a measure of drug’s efficacy
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 33 of 52
Side effects of sulphonylureas are less than those of biguanides. This considerations is:
A
TRUE
B
FALSE
C
All of the above
D
None of the above
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 34 of 52
This drug blocks inactivated (but not activated) Na+ channels.
A
Mexiletine
B
Phenytoin
C
Procainamide
D
Quinidine
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 35 of 52
Mr Khamis, 60 years old, has severe chest pain when he uses the stairs for more than one floor. The pain disappears when he rests. You prescribed the following drug to relieve the chest pain:
A
Nitroglycerine
B
Propranolol
C
Verapamil
D
Hydralazine
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 36 of 52
Which of the following inhaled anesthetics is an induction agent of choice in patient with airway problems?
A
Desfurane
B
Nitrous oxide
C
Halothane
D
None of the above
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 37 of 52
During a home visit with a patient diagnosed with schizophrenia the patient tells the community health nurse, “I’m going to stop going to the clinic for my fluphenazine decanoate (Prolixin) shots because I think I’m okay now.†Which statement represents the best understanding of the effect of the patient’s decision on the prognosis?
A
“So you think you’re okay now. Let’s discuss why you’ve decided to stop taking your medication.â€Â
B
“Your doctor knows what’s best for you. Just look at how well you’re feeling now so don’t stop taking the medication.â€Â
C
“It’s true that our philosophy is to use the least amount of medicine that is needed to treat a problem. Tell me why you think that you are okay now.â€Â
D
“I’m afraid that you’ll be sick again very soon if you aren’t taking your medication, but you are an adult and entitled to make your own decisions.â€Â
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 38 of 52
Therapeutic dose of digoxin in a normal individual has the following effects, except
A
Increase in the speed of myocardial contractility
B
No significant change in cardiac output
C
Relaxation of peripheral vascular bed
D
Increase in the force of myocardial contractility
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 39 of 52
A 75-year-old man with a history of intermittent angina presents to his primary physician. The anginal attacks are becoming more frequent, and therapy is considered for this reason. His blood pressure is 160/95 mm Hg. Which of the following agents would be least likely to be administered as a first-line agent for this patient?
A
Diltiazem
B
Nifedipine
C
Nitroglycerine
D
Ranolazine
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 40 of 52
Mineralocorticoid effects cause:
A
Increased catabolism
B
Increased Na retention and K excretion
C
Increased gluconeogenesis
D
Deposition of fat on shoulders, face and abdomen
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 41 of 52
The toxic effects of a large dose of nicotine include all of the following EXCEPT:
A
Hypotension and bradycardia
B
Convulsions coma and respiratory arrest
C
Skeletal muscle depolarization blockade and respiratory paralysis
D
Hypertension and cardiac arrhythmias
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 42 of 52
A patient has been taking chlorpromazine (Thorazine) for the past 2 weeks. He drools, has hand tremors, and walks with a shuffling gait. The nurse would correctly attribute these behaviors to:
A
Akinesia
B
Tardive dyskinesia
C
Pseudoparkinsonism
D
Neuroleptic malignant syndrome
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 43 of 52
During slow wave sleep (stage 3 and 4 NREM sleep):
A
Dreams occur
B
The secretion of adrenal steroids is at its highest
C
Somnambulism and nightmares occur
D
The secretion of somatotropin is at its lowest
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 44 of 52
A 55-year-old woman with a long history of poorly controlled essential hypertension had recently added atenolol to her therapeutic regimen. Which of the following was most likely a primary mechanism that mediated the antihypertensive effect of atenolol in this patient?
A
Dilation of large veins
B
Inhibition of epinephrine release from the adrenal medulla
C
Blockade of beta receptors of the vascular wall
D
Decreased sympathetic outflow from vasomotor area
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 45 of 52
Neuromuscular blockade by both succinylcholine and mivacurium may be prolonged in patients with:
A
Renal failure
B
An abnormal variant of plasma cholinesterase
C
Hepatic disease
D
Both b and c
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 46 of 52
All of the following statements concerning the general principles of therapy with lipid-lowering drugs are true EXCEPT:
A
Therapy with a lipid-lowering drug should be always accompanied by an appropriate diet
B
A lipid-lowering diet should be discontinued if it fails to decrease the levels of plasma LDL cholesterol by at least 10%
C
Lipid-lowering drugs should only be administered after at least 3 months of prior dietary therapy
D
Some combinations of lipid-lowering drugs are synergistic
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 47 of 52
Which drug is an analog of prostaglandin E1?
A
Misoprostole
B
De-nol
C
Sucralfate
D
Omeprazole
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 48 of 52
Which of the following drugs is an angiotensin converting enzyme inhibitor:
A
Enalapril
B
Diltiazem
C
Prazosin
D
Nifedipine
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 49 of 52
Which of the following local anesthetics is a short-acting drug?
A
Procaine
B
Tetracaine
C
Bupivacaine
D
Ropivacaine
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 50 of 52
Limitation of buspirone is:
A
A low therapeutic index
B
An extremely slow onset of action
C
A high potential of development of physical dependence
D
Impairment of mentation or motor functions during working hours
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 51 of 52
A patient with the diagnosis of schizophrenia is hospitalized and is taking a phenothiazine drug. Which statement by this patient indicates that he is experiencing a common adverse effect of phenothiazines?
A
“I can’t sleep at night.â€Â
B
“I feel hungry all the time.â€Â
C
“Look at how red my hands are.â€Â
D
“My mouth has been so dry lately.â€Â
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HESI LPN · HESI Learning Cardiovascular Drugs Pharmacology
Question 52 of 52
Beta-blocking agents have all of the following effects except:
A
Increase plasma concentrations of HDL and decrease of VLDL
B
Bronchoconstriction
C
Decrease of aqueous humor prodaction
D
“membrane-stabilizing†action
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