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Question 1 of 104
Pilocarpine is used in treatment of:
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Question 2 of 104
Which antiepileptic drug would be most appropriate for the 54-year-old man with complex partial seizure, atrioventricular block, and nephrolithiasis?
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Question 3 of 104
Beta agonists are commonly prescribed for the management of:
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Question 4 of 104
Which of the following adverse effects were most likely to occur during the first days of therapy with sertraline and diazepam?
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Question 5 of 104
Which of the following drugs is most commonly used for prophylaxis of migraine?
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Question 6 of 104
What is the major mechanism of action of the drug that apparently caused the patient's signs and symptoms?
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Question 7 of 104
Several children at a summer camp were hospitalized with symptoms thought to be due to ingestion of food containing botulinum toxins. The effects of botulinum toxin are likely to include
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Question 8 of 104
The cardiac muscarinic receptors
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Question 9 of 104
All of the following are ß-adrenergic agonists EXCEPT:
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Question 10 of 104
The action of acetylcholine is very short due to:
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Question 11 of 104
Atropine has the following side effects EXCEPT:
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Question 12 of 104
Muscarinic agonist used for atonic bowel or bladder:
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Question 13 of 104
Which of the following adverse effects most likely occurred in the patient who received a standard dose of morphine intramuscularly?
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Question 14 of 104
78-year-old male with Parkinson's disease experiences Parkinson's worsening of his symptoms. He is already taking levodopa. Since the disease is characterized by degeneration of dopaminergic neurons, leading to the lack of inhibition of cholinergic neurons, the addition of which medication is likely to help alleviate the patient's symptoms?
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Question 15 of 104
The synaptic pre-ganglionic neurons have their cell bodies in the lateral horn of the grey matter of the
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Question 16 of 104
A patient is admitted to the emergency room with orthostatic hypotension and evidence of marked GI bleeding. Which of the following most accurately describes the probable autonomic response to this bleeding?
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Question 17 of 104
Which of the following drugs would be most appropriate to treat the patient's urinary symptoms?
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Question 18 of 104
Which of the following analgesic drugs would be contraindicated for the patient with occlusive atherosclerotic disease of the legs?
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Question 19 of 104
Which of the following drugs most likely caused the patient's syndrome?
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Question 20 of 104
Which of the following adrenoreceptor antagonists has partial agonist activity and also membrane stabilizing activity
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Question 21 of 104
The drug that produces neuromuscular blockade by persistent depolarization is
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Question 22 of 104
Clinical uses of Vitamin D do not include
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Question 23 of 104
Dobutamine is used in treatment of:
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Question 24 of 104
ß1 receptors are present in
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Question 25 of 104
Quinidine, is a drug used for arrhythmias. One of its properties is strong postsynaptic alpha-adrenergic receptor blocking activity. What side effect would you expect as a result of this property?
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Question 26 of 104
Which of the following drugs was she most likely taking?
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Question 27 of 104
Hyoscine produces all of the following actions EXCEPT:
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Question 28 of 104
$α-1$ adrenergic receptors is selectively blocked by:
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Question 29 of 104
A 62-year-old man complained to his physician of facial grimacing, lip smacking, and rocking of the trunk that occurred 1 to 2 hours after taking his prescribed medication. The man, who suffered from Parkinson disease, had been receiving an antiparkinson drug for 3 years. Which of the following drugs most likely caused the adverse effects reported by the patient?
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Question 30 of 104
Propranolol does not block the following action of adrenaline
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Question 31 of 104
Postural hypotension is a common adverse effect of which one of the following types of drugs ?
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Question 32 of 104
Which of the following α-adrenoceptor blockers has the minimal hepatic biotransformation?
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Question 33 of 104
Which of the following drugs would be relatively contraindicated for a patient diagnosed with generalized anxiety disorder?
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Question 34 of 104
Hyoscine is one of the most effective drugs for preventing motion sickness, but may cause photophobia or blurred vision. Which is the most similar prototype drug?
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Question 35 of 104
Which of the following drugs was most likely prescribed for the 23-year-old woman with anxiety and cognitive difficulties?
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Question 36 of 104
Which of the following drugs was most likely given to the 65-year-old woman undergoing hysterectomy to counteract tubocurarine-induced hypotension?
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Question 37 of 104
What is composition of vagus nerve?
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Question 38 of 104
Which of the following cholinesterase inhibitors is said to produce more severe muscarinic side effects
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Question 39 of 104
ß-blockers
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Question 40 of 104
Ephedrine is similar to adrenaline in the following feature
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Question 41 of 104
Which one of the following is a cardio selective $ß1$-blocker:
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Question 42 of 104
Which of the following was most likely the disorder suffered by the patient's father?
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Question 43 of 104
Which of the following is most likely the common mechanism underlying the therapeutic effectiveness of long-term therapy with most antidepressants drugs?
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Question 44 of 104
A 33-year-old woman becomes poisoned after receiving an injection of concentrated botulinum toxin. Which of the following is the main neurochemical mechanism by which this Clostridium toxin causes its effects?
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Question 45 of 104
Injecting cocaine may cause a hypertensive crisis or stroke and if the cocaine is inhaled frequently it may destroy the tissues in the nose. Which of the following best describes how cocaine causes these adverse effects?
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Question 46 of 104
Which of the following drugs would be most appropriate for this patient to substitute for valproic acid therapy?
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Question 47 of 104
Which of the following drugs selectively stimulates $ß2$ adrenoceptors:
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Question 48 of 104
Which of the following drugs was most likely administered to the patient who developed muscle rigidity, tachycardia, and high fever during surgery?
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Question 49 of 104
Activation of sympathetic system leads to except
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Question 50 of 104
A 54-year-old man had been receiving carbamazepine since he was diagnosed with complex partial seizures 5 years earlier. The drug was fully effective in controlling the seizures. Blockade of which of the following molecular targets most likely mediated the therapeutic effect of the drug in the patient's disease?
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Question 51 of 104
Organophosphate insecticides and nerve gases exert their lethal effects by:
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Question 52 of 104
Which of the following drugs would be most appropriate for this patient?
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Question 53 of 104
Preferential beta1 adrenergic blocking agent is
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Question 54 of 104
Which of the following local anesthetics would be most appropriate for a 4-day-old boy with methemoglobinemia?
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Question 55 of 104
Glycopyrrolate is the preferred antimuscarinic drug for use before and during surgery because
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Question 56 of 104
From which of the following drugs was the man most likely experiencing withdrawal?
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Question 57 of 104
Which of the following adverse effects is most likely to occur during the therapy?
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Question 58 of 104
Selective beta2 stimulants frequently cause:
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Question 59 of 104
A 46-year-old woman complained of daytime sleepiness after taking an antihistamine for allergic rhinitis. Which of the following brain regions was most likely involved in the adverse effect of this drug?
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Question 60 of 104
Which of the following drugs has muscarinic and nicotinic actions and is resistant to hydrolysis by both true and pseudo cholinesterase:
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Question 61 of 104
Select the correct statement from the following about α1- adrenergic receptor agonists
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Question 62 of 104
Cromolyn has as its major action
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Question 63 of 104
Dihydroergotamine differs from ergotamine in the following respect
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Question 64 of 104
Giving a single IV injection of phenylephrine can be used to normalize a rapid heart rate in paroxysmal supraventricular tachycardia (PSVT). How does phenylephrine do this?
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Question 65 of 104
A child overdoses on a drug that affects both the autonomic and somatic nervous systems. As blood level of the drug rises he experiences hypertension and tachycardia, accompanied by skeletal muscle tremor. Further elevations of the drug cause all the expected signs and symptoms of autonomic ganglionic blockade, plus weakness and eventual paralysis of skeletal muscle. Which of the following drugs did the child most likely ingest?
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Question 66 of 104
The drug which produces vasoconstriction despite being an α adrenergic blocker is
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Question 67 of 104
The site of action of d-tubocurarine is
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Question 68 of 104
Which of the following drugs was most likely prescribed for decreasing reuptake of both norepinephrine and dopamine by brain neurons?
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Question 69 of 104
Which of the following is a typical effect of the parasympathetic nervous system activation?
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Question 70 of 104
Which of the following effects of epinephrine would be blocked by phentolamine but not by metoprolol?
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Question 71 of 104
Isoprenaline produces the following actions EXCEPT:
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Question 72 of 104
Adrenaline can produce all of the following effects EXCEPT:
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Question 73 of 104
What type of receptor does acetylcholine primarily bind to at the neuromuscular junction?
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Question 74 of 104
Which of the following actions most likely mediate the adverse effect reported by the patient?
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Question 75 of 104
The most appropriate drug for treating myasthenia gravis is:
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Question 76 of 104
The order of paralysis with d-tubocurarine is
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Question 77 of 104
Muscarinic receptors are G-protein coupled receptors, causing
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Question 78 of 104
Metoprolol is a cardioselective beta blocker (relatively selective beta1 - blocker)
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Question 79 of 104
Regarding parasympatholytics, the following statement is WRONG:
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Question 80 of 104
Which of the following would be the minimum alveolar concentration of both drugs needed to provide an appropriate general anesthesia in this patient?
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Question 81 of 104
Match each of the nerves listed on the left with their corresponding zone of innervation from the drop list on the right:
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Question 82 of 104
Which of the following types of drugs would be most appropriate to provide immediate relief to this patient?
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Question 83 of 104
Which of the following drugs would be contraindicated for a patient undergoing major surgery to remove a breast carcinoma who has chronic obstructive pulmonary disease and is a heavy smoker?
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Question 84 of 104
A 16-year-old-girl is found to have paroxysmal attacks of rapid heart rate. The antiarrhythmic of choice in most cases of acute AV nodal tachycardia is
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Question 85 of 104
Low doses of adrenaline dilate the following vascular bed
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Question 86 of 104
Which of the following psychotropic drugs would be most appropriate to try at this stage for the 29-year-old man with chronic paranoid schizophrenia?
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Question 87 of 104
Concerning physostigmine, which of the following is CORRECT:
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Question 88 of 104
Which of the following receptors most likely mediated the adverse effects of the drug in the patient?
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Question 89 of 104
At rest, the interior of the typical mammalian neuronal axon potential is approximately mV
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Question 90 of 104
N. mandibularis is:
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Question 91 of 104
The major common determinant of myocardial oxygen consumption is
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Question 92 of 104
Intravenous administration of epinephrine to a patient results in a severe decrease in diastolic pressure and an increase in cardiac output. Which of the following drugs might the patient have previously taken that could account for this unexpected effect?
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Question 93 of 104
Which of the following is a long-acting beta-2 agonist commonly used in the management of asthma and COPD?
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Question 94 of 104
Which of the following diuretics would be most useful in a patient with cerebral edema?
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Question 95 of 104
Which of the following drugs would be appropriate for the patient planning to become pregnant?
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Question 96 of 104
Which of the following is a vasodilator drug used for hypertension that lacks a direct effect on autonomic receptors but may provoke anginal attacks?
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Question 97 of 104
Which of the following drugs would be useful to treat the patient's condition of repeated head jerking, blinking, and grimacing?
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Question 98 of 104
A 7-years-old boy has a significant bedwetting problem. A long-acting indirect sympathomimetic agent sometimes used by the oral route for this and other indications is
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Question 99 of 104
The motor fibers of n. vagus originate from:
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Question 100 of 104
Which of the following statements about anticholinesterase drugs is WRONG:
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Question 101 of 104
Which of the following cardiovascular actions most likely contributed to the therapeutic effect of morphine in the patient's disorder?
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Question 102 of 104
A 10-year-old boy is diagnosed with Attention Deficit/Attention Deficit-Hyperactivity disorder (AND/ADHD). Which of the following drugs is most likely to prove effective for relieving the boy's main symptoms?
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Question 103 of 104
Phenylephrine has most prominent
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Question 104 of 104
The following terminal nerves originate from fasciculus posterior (plexus brachialis):
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