HESI CNS Stimulants Drugs Pharmacology Quiz

HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 1 of 107

The drug of choice in the treatment of organophosphorus poisoning is

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Question 2 of 107

A 47-year-old man is given atropine to decrease dental secretions during a root canal procedure. This agent is most likely to have an effect on which of the following target organs/glands?

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Question 3 of 107

A 49-year-old man with manic depression has been maintained on lithium for long-term therapy. However, because of worsening of symptoms, he is placed on ziprasidone. The patient must be warned about which of the following adverse effects?

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Question 4 of 107

Which of the following local anesthetics is poorly water-soluble PABA derivative and primarily used for anorectal lesions, wounds, and ulcers?

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Question 5 of 107

Symptoms of acute morphine toxicity include:

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Question 6 of 107

The following drug is used for short-term control of emergency heart failure but not for long-term treatment of CHF

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Question 7 of 107

A vasoconstrictor is added to local anaesthetic for

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Question 8 of 107

A 52-year-old man who depends upon his three cups of coffee per day, which he purchases at his place of work, suddenly finds that the coffee stand has closed. He now is unable to drink his three cups of coffee per day. Which of the following effects might he exhibit at work?

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Question 9 of 107

A 70-year-old man with hypertension and decreased urinary flow presents to his primary care physician for treatment of his urinary symptoms. His current medications include a calcium channel blocker. Physical examination reveals a 20-g prostate without nodules. Which of the following is the most efficacious treatment for this patient with minimal potential for adverse events?

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Question 10 of 107

Kinins play a role in which of the following

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Question 11 of 107

In the GI tract, enterochromaffin cells are maximum in

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Question 12 of 107

A 15-year-old boy attempts suicide and is brought to the emergency department by the local rescue squad. He was found in the garage with an opened spray bottle of insecticide nearby. He has lost consciousness. His heart rate is 45 beats/minute, and his blood pressure is 80/40 mm Hg. He is sweating and salivating profusely. What is the most appropriate treatment for this patient?

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Question 13 of 107

Which one of the following statements best describes the mechanism of action of benzodiazepines?

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Question 14 of 107

Which lithium salt is used for manic depressive disorders?

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Question 15 of 107

Opioid analgesics inhibit the release of which of the following hormones?

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Question 16 of 107

The primary mechanism of action of benzodiazepine is

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Question 17 of 107

Pentazocine differs from morphine in that

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 18 of 107

A patient has been received a large dose of one of the non-steroidal anti-inflammatory drugs for a long period, developed tinnitus, blurring of vision, GIT upset, irritability and hyperventilation. Fortunately, these symptoms and signs were reversible after stopping the drug. Which of the following drugs was the most likely cause of these adverse effects?

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Question 19 of 107

All the following are complications of large doses of glucocorticoids, EXCEPT:

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Question 20 of 107

Neostigmine is preferred over physostigmine for treating myasthenia gravis because

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Question 21 of 107

Which of the following benzodiazepines is expected to cause the least amount of adverse effects in the elderly?

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Question 22 of 107

Cyclooxygenase-1 and -2 are responsible for

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 23 of 107

A 59-year-old man presents to his primary care physician with an extremely sore shoulder following an accident at work. He is not found to have any fractures or tears and is treated with an injection of prednisolone for bursitis. He smokes and is currently taking levothyroxine because of a thyroidectomy, a ÃƒÅ½Ã‚Â²-blocker for mild heart failure, and prazosin for benign prostatic hyperplasia. His medications and the nicotine in his cigarettes each act on a different receptor. Activation of which of the following receptors produces the fastest cellular response?

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Question 24 of 107

Which statement about thiopentone is true?

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Question 25 of 107

Which of the following extra-pyramidal effects seen with antipsychotic agents is also known as rabbit syndrome?

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Question 26 of 107

Norepinephrine in the synaptic cleft can activate presynaptic alpha 2 receptors which results in

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Question 27 of 107

Which of the following best describes appropriate protocols for withdrawal of glucocorticoids from a patient who has been taking large doses for 6 months?

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Question 28 of 107

A 53-year-old woman with seizure disorder, bipolar disorder, and trigeminal neuralgia presents to her primary care physician for follow-up and treatment. She has no new complaints. Which of the following medications may serve to treat all of her earlier mentioned problems?

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Question 29 of 107

Which of the following steroids has a powerful sodium retaining effect:

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Question 30 of 107

The nonsteroidal anti-inflammatory drug which is contraindicated in drivers and machine operators is

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 31 of 107

Suxamethonium

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 32 of 107

Which one of the following drugs is most likely to cause hypoglycemia when used as monotherapy in the treatment of type 2 diabetes?

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 33 of 107

Which of the following bones is affected more by glucocorticoid-induced osteoporosis?

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 34 of 107

The following are useful in management of an acute attack of gout EXCEPT:

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Question 35 of 107

Tolcapone is an antiparkinsonian agent that inhibits which of the following enzymes in brain?

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 36 of 107

Which one of the following statements about phenytoin is accurate?

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Question 37 of 107

The following prostanoid is a potent inducer of platelet aggregation

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Question 38 of 107

A young woman was diagnosed to have endometriosis. The most appropriate therapy for this patient would be:

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 39 of 107

Following is a GABA_A agonist

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 40 of 107

The most important therapeutic indication of acetazolamide is

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Question 41 of 107

The estrogen that is used in most combined hormonal contraceptives is:

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 42 of 107

Morphine is contraindicated in head injury because

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Question 43 of 107

Regarding ginkgo, the correct statement is

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 44 of 107

The following drugs are useful in management of gout EXCEPT:

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 45 of 107

Which of the following is an intravenous anaesthetic

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Question 46 of 107

Side effects of MAO inhibitors include the following EXCEPT:

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Question 47 of 107

A 79-year-old man undergoes a hip replacement procedure under general anesthesia and is unable to be weaned from the ventilator postoperatively. Review of the anesthesia records indicated that he received the following agents: succinylcholine, diazepam, rocuronium, and fentanyl. He spends the next 5 days on a ventilator in the intensive care unit. Which of the following is the most likely explanation for this situation?

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 48 of 107

The primary endogenous substrate for nitric oxide synthase is

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 49 of 107

The drug effective for gouty arthritis via two distinct mechanisms is

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Question 50 of 107

Which of the following drugs has been found to reduce alcohol craving and chances of resumed heavy drinking by alcoholics after they have undergone a detoxification program

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 51 of 107

Neuronal death in response to high glutamate concentration is mediated by

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 52 of 107

A 56-year-old male is on numerous medications, many of which are metabolized by the cytochrome P-450 system. He went to the psychiatric with depression. Given his multiple medications, which of the following antidepressant drugs should be avoided?

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Question 53 of 107

This drug, which does not activate opioid receptors, has been proposed as a maintenance drug for opioid addicts.

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Question 54 of 107

The most common sign/symptom of hemorrhoids is

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Question 55 of 107

The most important channel of elimination of digoxin is

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Question 56 of 107

Compared to other antipsychotic drugs, the distinctive feature of penfluridol is

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Question 57 of 107

Which of the following statements most closely describes the current status of angiotensin-converting enzyme inhibitors in congestive heart failure?

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Question 58 of 107

The most important reason for the unpopularity of nonselective MAO inhibitors as antidepressants is their

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 59 of 107

Which statement about benzodiazepines is correct?

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 60 of 107

Prolonged lithium therapy can cause

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HESI LPN · HESI CNS Stimulants Drugs Pharmacology Quiz

Question 61 of 107

The metabolism of ethanol is directly proportional to

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Question 62 of 107

What are the most common adverse effects of anticonvulsive drugs?

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Question 63 of 107

The anti-diuretic action of vasopressin is mediated via

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Question 64 of 107

Which one of the following signs or symptoms is likely to occur with marijuana?

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Question 65 of 107

A 71-year-old man with gradual impairment in short-term memory and speech is thought to have Alzheimer's disease. His primary care physician begins him on rivastigmine. This agent will most likely cause which of the following effects?

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Question 66 of 107

Which of the following compounds is most likely to lower circulating levels of leukotrienes?

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Question 67 of 107

Which of the following conditions is an indication for the use of raloxifene?

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Question 68 of 107

Which of the following parenteral local anaesthetics has a short duration of action (i.e. between 30 to 60 minutes)

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Question 69 of 107

Following is an excitatory amino acid receptor antagonist?

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Question 70 of 107

The term endorphin refers to which of the following?

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Question 71 of 107

The local anaesthetic with a short duration of action is

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Question 72 of 107

Phenobarbitone is beneficial in the treatment of which of the following generalized seizures

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Question 73 of 107

Hydroxyethyl starches

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Question 74 of 107

A 49-year-old man with long-standing schizophrenia is hospitalized for a symptom exacerbation. His primary care physician places him on a second-generation antipsychotic agent. Characteristics of this agent include which of the following?

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Question 75 of 107

Which of the following would be the drug of choice for treatment of hypertensive crisis?

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Question 76 of 107

Anti-convulsant drugs include which of the following:

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Question 77 of 107

Which of the following adverse effects of levodopa has a delayed onset and increases in severity with continued therapy?

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Question 78 of 107

An overdose victim presents with an elevated heart rate, decreased blood pressure, dilated pupils, and lethargy, followed by a tonic-clonic seizure. Which is the most likely intoxicant?

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Question 79 of 107

Which diuretic is orally active, works in both acidosis and alkalosis, is effective in renal failure, and has carbonic anhydrase inhibitory action?

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Question 80 of 107

The factor that affects the rate of elimination of general anesthetics is

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Question 81 of 107

A 32-year-old forklift operator with a past history of cardiac arrhythmias is suffering from seasonal rhinitis. Which of the following choices is the best recommendation for this patient?

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Question 82 of 107

Which drug is a monoamine oxidase inhibitor used to treat hypertension?

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Question 83 of 107

Which of the following mood stabilizers would be most appropriate in a patient with liver disease?

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Question 84 of 107

The following drug has been found to improve urine flow in elderly males with benign prostatic hypertrophy

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Question 85 of 107

A 33 year old lady with type 2 diabetes mellitus presents in early pregnancy. Which of the following is most appropriate?

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Question 86 of 107

Drugs useful to initiate sleep include which of the following:

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Question 87 of 107

A 68-year-old woman with a long history of sadness, gloom, and weight loss presents to her primary care physician for treatment. She is treated with a selective serotonin reuptake inhibitor. Which of the following statements is true?

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Question 88 of 107

Probenecid has the following action(s)

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Question 89 of 107

The most serious effect of morphine poisoning is:

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Question 90 of 107

Five patients present to their primary care physician with various complaints and problems. Which of the following patients would have the most limited response to their symptoms if given a prescription for diazepam?

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Question 91 of 107

Which of the following diseases is worsened by propranolol?

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Question 92 of 107

The antihypertensive drug most likely to aggravate angina pectoris is

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Question 93 of 107

An 83-year-old man is brought to the clinic by his family with complaints stating he can no longer perform his daily activities or be trusted to live on his own. During his neurological exam, he presents with moderate memory loss, apraxia, and anomia. Also, he displays aggressive behaviors throughout the physical exam. He was diagnosed to be in an early stage of Alzheimer's disease. What class of drugs would be most helpful in treating the patient?

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Question 94 of 107

Which of the following was the first compound to be identified pharmacologically as a transmitter in the CNS?

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Question 95 of 107

Which of the following drugs, is an insulin sensitizer:

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Question 96 of 107

The barbiturate having a higher anticonvulsant-to-sedative activity ratio is

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Question 97 of 107

Which of the following MAO inhibitors prevents the 1-methyl 4-Phenyl 1,2,3,6 tetrahydropyridine's (MPTP) selective action in destroying the dopaminergic nigro-striatal neurons?

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Question 98 of 107

Corticosteroid therapy is practically mandatory in the following condition

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Question 99 of 107

Which of the following statements about pramipexole is accurate?

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Question 100 of 107

A 54-year-old male patient was using fluoxetine for depression but decided to stop taking the drug. When questioned, he said that it affected his sexual performance and that he wasn't getting any younger. You notice that he is a user of tobacco products. If you decide to reinstitute drug therapy in this patient, the best choice would be

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Question 101 of 107

Methanol is toxic to the optic nerve. It is because of

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Question 102 of 107

Clobazam is a benzodiazepine used as

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Question 103 of 107

A 27-year-old woman with amenorrhea, infertility, and galactorrhea was treated with a drug that successfully restored ovulation and menstruation. Before being given the drug, the woman was carefully questioned about previous mental health problems, which she did not have. The drug used to treat this patient was probably:

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Question 104 of 107

Which of the following should not be administered to a patient with myasthenia gravis?

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Question 105 of 107

A young mother is breast-feeding her 2-month-old infant. Which one of the following drug situations involving the mother is most likely to be safe for the nursing infant?

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Question 106 of 107

Which of the following neuromuscular blocking agents has a short duration of action?

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Question 107 of 107

Benzodiazepines are least effective in

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