HESI Chapter 2 pharmacologic principles

HESI LPN · HESI Chapter 2 pharmacologic principles

Question 1 of 50

Cross MATCH each drug to the most suitable indication: Constipation with impacted stool

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 2 of 50

Which of the following functional groups is most susceptible to hydrolysis?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 3 of 50

Cyclophosphamide:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 4 of 50

The following are used to treat Pneumocystis carinii pneumonia (PCP) in patients with HIV infection:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 5 of 50

Tetracyclines are used to treat:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 6 of 50

Dapsone:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 7 of 50

Amoxicillin:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 8 of 50

Cross Match each of the following adverse effect to the corresponding drug: Aplastic anemia & bleeding

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 9 of 50

Which of the following radionuclides is generator produced?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 10 of 50

Which of the following is WRONGLY matched to its drug?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 11 of 50

Represents rate & extent of drug absorption as measured by area under curve

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 12 of 50

Which of the following drugs may inhibit the hepatic microsomal P450 responsible for warfarin metabolism

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 13 of 50

A 61-year-old man is taking over-the-counter pseudoephedrine for cold and flulike symptoms. Over the course of the next few days, he experiences improvement in his rhinitis but should be concerned about the possibility of which of the following problems?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 14 of 50

Active transport differs from facilitated transport in following ways, except

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 15 of 50

The following drugs are effectively administered via the sublingual route:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 16 of 50

The colligative properties of a solution are related to the

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 17 of 50

Wrong statement concerning pharmacokinetics of H2-receptor antagonists is

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 18 of 50

All the following are adverse effects of metoclopramide except

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 19 of 50

Cross Match: Venlafaxine

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 20 of 50

Foscarnet:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 21 of 50

The pharmacokinetic 'elimination half-life' of the following drugs mirrors their pharmacodynamic duration and intensity of action:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 22 of 50

Urticaria that appears rapidly after the ingestion of food usually indicates which type of hypersensitivity reaction?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 23 of 50

Flurazepam has pKa of 8.2. What percentage of flurazepam will be ionized at a urine pH of 5.2 ?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 24 of 50

The following concerning naloxone is not correct:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 25 of 50

Cross MATCH each drug to its specific feature in management of diarrhea: Diphenoxylate

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 26 of 50

Which of the following agents is a prodrug that is much less toxic in mammals than in insects?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 27 of 50

A 59-year-old man with decreased urinary stream and hypertension is prescribed doxazosin in hopes that both problems will be treated. He begins dose escalation with $1 \mathrm{mg}$ given for one week, $2 \mathrm{mg}$ given for 2 weeks, and $4 \mathrm{mg}$ given for maintenance. He returns to his primary care physician saying that this medication is not helping. To determine whether or not the patient is taking the medication, it would be useful to look at the excreted concentration of medication in which of the following areas?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 28 of 50

A 59-year-old female with diabetes presents to her primary care physician for routine follow-up. Her current medications include insulin. Her fasting blood sugars are in the range of 80 to $120 \mathrm{mg} / \mathrm{dL}$. The intracellular effects of this medication are likely caused by which of the following mechanisms of action?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 29 of 50

In vomiting due to motion sickness, the following is (are) used

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 30 of 50

Most serious adverse effect/s of morphine

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 31 of 50

The sugar that is inherent in the nucleic acids RNA and DNA is

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 32 of 50

The renal clearance of insulin is used as a measurement of

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 33 of 50

Lopinavir, an HIV-protease inhibitor, is associated with the following:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 34 of 50

Which of the following is preferred for treatment of anxiety with panic attacks:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 35 of 50

Which of the following analgesic agents poses a risk in a 60 -year-old patient with a history of transient ischemic attacks

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 36 of 50

The following drugs undergo phase II metabolism by hepatic acetylation enzymes (N-acetyltransferases):

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 37 of 50

The following are excreted faster in basic urine

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 38 of 50

An 18-year-old college student is hanging shelves in his dorm room. He accidently hits his thumb with the hammer, which subsequently becomes swollen and red. He takes some acetaminophen for the pain. Many proteins are activated in response to injury leading to inflammation. Which of the following proteins is a transcription factor?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 39 of 50

Indomethacin is least likely to be prescribed in

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 40 of 50

For each description of a comminution procedure below, select the process that it best describes

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 41 of 50

A hospitalized patient with systemic candidiasis is receiving intravenous antifungal medications. He also has hepatic and renal insufficiency. Which of the following drug administration schemes would allow for the most steady state amount of drug in the body over a 2-week hospitalization period where medication administration will be necessary?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 42 of 50

When drug/drug interactions involve inhibition of metabolism, which of the following types of drugs are of the most concern?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 43 of 50

The following statements concerning renal drug handling are correct:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 44 of 50

The following drugs undergo significant enterohepatic circulation:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 45 of 50

Dose dumping is a problem in the formulation of

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 46 of 50

Drugs with small volume of distribution (Vd) are characterized by

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 47 of 50

Indications of antidepressants do not include:

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 48 of 50

Which capsule size has the smallest capacity?

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 49 of 50

Abuse potential of buspirone is low because

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HESI LPN · HESI Chapter 2 pharmacologic principles

Question 50 of 50

Which of the following statements is/are True?

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