HESI Central and Peripheral Nervous System Drugs

HESI LPN · HESI Central and Peripheral Nervous System Drugs

Question 1 of 102

Belladonna poisoning is best treated with

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Question 2 of 102

Which one of the following is characteristic of captopril and enalapril ?

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Question 3 of 102

A sympathomimetic amine that acts almost exclusively by releasing noradrenaline from the nerve endings is

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Question 4 of 102

A 54-year-old woman suffering from initial insomnia was prescribed a hypnotic drug that increases the activity of a major neurotransmitter system in the brain. Which neurotransmitter system was most likely involved in the therapeutic action of that drug?

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Question 5 of 102

A practical test to differentiate between myasthenia crisis and cholinergic crisis is by injecting the patient:

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Question 6 of 102

Which of the following drugs was most likely prescribed?

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Question 7 of 102

Beta blockers are contraindicated in patients with which condition?

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Question 8 of 102

Which of the following muscle relaxants was most likely given to a patient who exhibited transient muscle fasciculations that progressed to generalized paralysis within 1 minute of administration?

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Question 9 of 102

Which of the following has the longest half-life of all antiarrhythmic drugs?

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Question 10 of 102

The anterior ramus of spinal nerve C7:

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Question 11 of 102

This drug is effective in all forms of epilepsy in all age groups.

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Question 12 of 102

Which of the following signs and symptoms did the girl most likely experience just after smoking?

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Question 13 of 102

Which of the following has no muscarinic blocking activity:

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Question 14 of 102

Atropine is contraindicated in

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Question 15 of 102

All of the following are cardiovascular actions of noradrenaline EXCEPT:

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Question 16 of 102

A 54-year-old woman with a previously well-controlled seizure disorder was brought to the hospital because of recurrent, generalized tonic-clonic seizures. The patient was intubated and mechanically ventilated. She was treated with intravenous diazepam and fosphenytoin but continued to exhibit intermittent seizures and did not regain consciousness between them. A diagnosis of refractory status epilepticus was made. A large dose of which of the following drugs would be appropriate to add to the patient's therapy at this time?

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HESI LPN · HESI Central and Peripheral Nervous System Drugs

Question 17 of 102

A 35-year-old female presents to your office for a regular check-up. Her only complaint is recurrent migraine headaches, which have increased in frequency over the years. On examination, her blood pressure is elevated at 150/70. You decide to start her on antihypertensive therapy that is also used for prophylaxis of migraines. Which medication is it?

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HESI LPN · HESI Central and Peripheral Nervous System Drugs

Question 18 of 102

When used as an antiarrhythmic drug, Lidocaine typically

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Question 19 of 102

Adrenaline can be used in the following EXCEPT:

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Question 20 of 102

Botulism is a serious and sometimes fatal disorder caused by Botulinum toxin. How is Botulinum toxin exerting its effects?

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Question 21 of 102

Which alpha blocker drug is commonly used to treat hypertension and glaucoma?

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Question 22 of 102

Adrenaline is contraindicated in:

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Question 23 of 102

Following are irreversible anti-cholinesterases, except

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Question 24 of 102

A drug that is useful in glaucoma and high-altitude sickness is

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Question 25 of 102

Which of the following molecular actions in the enteric nervous system most likely mediated the adverse effect of the drug in the patient?

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Question 26 of 102

To reduce the muscarinic side effects of oral forms of cholinesterase inhibitors they should be administered

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Question 27 of 102

A 38-year-old farmer is brought to the emergency room by his wife with symptoms of sudden difficulty breathing, sweatiness, and anxiety. He was spraying insecticide when this happened. It has been 25 minutes since the symptoms started. Patient is emergently intubated and given atropine and another medication that acts to reactivate acetyl cholinesterase. What medication is it?

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Question 28 of 102

Which of the following anticholinergic drugs is primarily used in preanesthetic medication and during surgery

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Question 29 of 102

Which instruction given to a patient taking a B-blocker is essential to reduce the chance of an adverse response to the B-blocker, regardless of the purpose for which it's been prescribed?

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Question 30 of 102

A 44-year-old woman was admitted to the psychiatric hospital for the sixth time since the age of 36. She was confused and threatening, saying that the voices are back. The woman had been on antipsychotic therapy for several years, but she of the patient's presenting symptoms

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Question 31 of 102

Which of the following neurotransmitters most likely mediated the effects of the drug in this patient?

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Question 32 of 102

Which of the following drugs most likely caused the patient's signs and symptoms?

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Question 33 of 102

Chemically following anti-cholinesterase is an alcohol

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Question 34 of 102

Which division of the autonomic nervous system is responsible for the 'fight or flight' response?

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Question 35 of 102

Which of the following variables most likely caused the decrease in MAC in this case?

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Question 36 of 102

Which of the following drugs is used as inhalation as a bronchodilator and may be used when cough is a pronounced symptom in asthmatic patient?

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Question 37 of 102

d-Amphetamine has most prominent

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Question 38 of 102

Propranolol is contraindicated / not beneficial in

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Question 39 of 102

ÃƒÅ¸-blockers are better avoided in

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Question 40 of 102

Which of the following conditions is an indication for the use of calcitonin?

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Question 41 of 102

Nervi splanchnici thoracici major, minor et imus (the major, minor and the least thoracic splanchnic nerves) are reaching the abdominal cavity through:

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Question 42 of 102

Which of the following drugs was most likely prescribed for the child unable to sit still in school?

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Question 43 of 102

Which of the following situations constitutes an added risk of digoxin toxicity?

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Question 44 of 102

Congenital dopamine-ÃƒÅ¸-hydroxylase deficiency is characterized by

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Question 45 of 102

Which of the following drugs most likely caused the patient's symptoms?

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Question 46 of 102

ÃƒÅ¸3 receptor is present in

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Question 47 of 102

Guanethidine inhibits

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Question 48 of 102

In relation to the molecular mechanism of action of sympathomimetics the following is CORRECT:

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Question 49 of 102

The antianginal effect of propranolol may be attributed to which one of the following

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Question 50 of 102

All the following adverse effects can be produced by beta-blockers EXCEPT:

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HESI LPN · HESI Central and Peripheral Nervous System Drugs

Question 51 of 102

Donepezil is a reversible anti-cholinesterase used in treatment of:

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Question 52 of 102

Atropine is used clinically in all of the following conditions EXCEPT:

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Question 53 of 102

Muscarinic cholinergic receptors

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Question 54 of 102

Which of the following was most likely one of the postreceptor mechanisms triggered by methadone?

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HESI LPN · HESI Central and Peripheral Nervous System Drugs

Question 55 of 102

Which of the following structures was most likely the site of therapeutic action of botulinum toxin injected into the ocular muscles of the 22-year-old man with strabismus?

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Question 56 of 102

Propanolol can be used to allay anxiety associated with

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Question 57 of 102

Which of the following drugs was most likely prescribed for the 12-year-old girl with extensive jaundice?

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HESI LPN · HESI Central and Peripheral Nervous System Drugs

Question 58 of 102

Which of the following drugs used for the treatment of angina by inhalation has a very rapid onset and a brief duration of effect?

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Question 59 of 102

Which of the following adverse effects was most likely to occur in the patient receiving local injections of botulinum toxin for benign essential blepharospasm?

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Question 60 of 102

Which of the following drugs would be contraindicated for the patient with cogwheel rigidity being treated with haloperidol?

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Question 61 of 102

Atropine overdose may cause which one of the following

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Question 62 of 102

A patient presents with an anaphylactic reaction following a bee sting. Which of the following is the drug of choice for treating the multiple cardiovascular and pulmonary problems that, if not promptly corrected, could lead to the patient's death?

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Question 63 of 102

The therapeutic effect of aripiprazole in the 28-year-old man with paranoid schizophrenia is most likely mediated by decreased dopaminergic transmission in which of the following brain structures?

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Question 64 of 102

Ergotamine relieves migraine by

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Question 65 of 102

Narcolepsy is treated with:

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Question 66 of 102

In relation to noradrenaline all of the following are true EXCEPT:

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Question 67 of 102

Following muscarinic agonist is susceptible to hydrolysis by cholinesterase

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Question 68 of 102

Propantheline can be used for the treatment of peptic ulcer disease because it decreases gastric acid secretion. What prototype drug is most like propantheline?

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Question 69 of 102

Which drug was most likely prescribed for the 44-year-old woman with poorly controlled simple partial seizures that was only partially effective with valproic acid?

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Question 70 of 102

Which one of the following ÃƒÅ¸- blockers has reduced risk of bronchospasm?

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Question 71 of 102

Each of the following parasympathomimetic drugs is correctly matched with an appropriate pharmacological action EXCEPT:

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Question 72 of 102

A child visiting his grandfather at his farm, returned home having fever, skin flush, dry mouth, constipation, dilated pupils and increased heart rate. Which of the following could be the offending agent:

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Question 73 of 102

N. lingualis is a branch of:

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Question 74 of 102

Centrally acting skeletal muscle relaxant is

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Question 75 of 102

Which wall of the tympanic cavity has canaliculi caroticotympanici, through which the sympathetic nerves from plexus caroticus internus enter?

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Question 76 of 102

Typical results of beta-receptor activation include which one of the following?

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Question 77 of 102

Which of the following symptoms did the patient most likely experience upon recovery from sedation?

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Question 78 of 102

A patient with Alzheimer's disease is taking an acetyl cholinesterase inhibitor specifically approved for that indication, primarily because it is quite lipophilic and so enters the CNS well. Which of the following drugs is the patient most likely receiving?

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Question 79 of 102

Which of the following neural pathways most likely represent the main site of therapeutic action of the drug in the 8-year-old boy diagnosed with ADHD?

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Question 80 of 102

Which drug would most likely be effective in decreasing the patient's spontaneous breathing?

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Question 81 of 102

Withdrawal from which of the following drugs most likely caused the patient's seizure?

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Question 82 of 102

Albuterol causes selective activation of B-2 adrenergic receptors when administered in 'low doses,' mainly by inhalation. If very large doses of albuterol were given, or if the drug is administered intravenously, the effects caused by albuterol would look quite different and would resemble those of which one of the following drugs?

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HESI LPN · HESI Central and Peripheral Nervous System Drugs

Question 83 of 102

Which of the following adverse effects would most likely occur after the administration of another dose of lidocaine near the brachial plexus for a peripheral nerve block?

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Question 84 of 102

Which of the following drugs was most likely prescribed for the patient with past episodes of depression and mania?

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Question 85 of 102

Pilocarpine is used in treatment of:

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Question 86 of 102

Full activation of the sympathetic nervous system, as in maximal exercise, can produce all of the following responses except

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Question 87 of 102

Pancuronium differs from tubocurarine in that

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Question 88 of 102

Which of the following neurotransmitters has been most consistently implicated in the patient's disorder?

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Question 89 of 102

What was most likely the reason for the adverse effects reported by the patient?

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Question 90 of 102

Which enzyme is responsible for breaking down acetylcholine in the synaptic cleft?

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Question 91 of 102

Which of the following drugs was most likely administered to the patient?

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Question 92 of 102

Which of the following drugs does not pass blood brain barrier:

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Question 93 of 102

Following agent inhibits the release of acetyl choline

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Question 94 of 102

A drug has a complex molecular mechanism of action that includes a blockade of presynaptic alphareceptors. Which of the following drugs was most likely given?

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Question 95 of 102

Dobutamine differs from dopamine in that

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Question 96 of 102

Which of the following drugs has the highest potency among the new potential inhalational anesthetics tested in laboratory animals?

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Question 97 of 102

A 59-year-old man complains of nocturia, urinary frequency, and an inability to urinate forcefully and empty his bladder. Following a complete workup, he was diagnosed as benign prostatic hypertrophy (BPH). We start daily therapy with tamsulosin. Which of the following is the most likely side effect the patient may experience from the tamsulosin, and about which he should be forewarned?

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Question 98 of 102

Pheochromocytoma is a tumor of the adrenal medulla. The tumor results in extraordinary high blood noradrenaline levels. What drug or drug combination can block all of adrenergic receptors and normalize all the signs and symptoms caused by pheochromocytoma?

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Question 99 of 102

Treatment of acute organophosphorus poisoning includes all of the following EXCEPT:

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Question 100 of 102

Which of the following drugs is the drug of choice in anaphylaxis associated with bronchospasm and hypotension?

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Question 101 of 102

Which of the following analgesic drugs would be contraindicated for the patient with postoperative adynamic ileus?

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Question 102 of 102

In male sex organs system is responsible for erection.

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