HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 1 of 52
Which of the following statements refers to gallium nitrate:
A
It is approved by the FDA for the management of hypercalcemia of malignancy
B
This drug acts by inhibiting bone resorption
C
Because of potential nephrotoxicity, patients should be well-hydrated and have good renal output before starting the infusion
D
All of the above
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 2 of 52
Which of the following phenothiazine derivatives is a potent local anesthetic?
A
Fluphenazine
B
Thioridazine
C
Chlorpromazine
D
None of the above
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 3 of 52
This drug has beta-adrenergic blocking activity:
A
Flecainide
B
Sotalol
C
Lidocaine
D
Verapamil
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 4 of 52
All of the following drugs are indirect acting anticoagulants EXCEPT:
A
Dicumarol
B
Warfarin
C
Dalteparin
D
Phenindione
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 5 of 52
Activation of dopamine D receptors
A
Furosemide
B
Hydralazine
C
Labetalol
D
Losartan
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 6 of 52
The Immunosuppressive agent is:
A
Corticosteroids
B
Cyclosporine
C
Tacrolimus (FK 506)
D
All of the above
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 7 of 52
Fibrinolysis is mainly carried out by
A
Tissue - type plasminogen activator
B
Urokinase - type plasminogen activator
C
Both (a) and (b)
D
None of the above
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 8 of 52
The limitation of sevoflurane is:
A
High incidence of coughing and laryngospasm
B
Chemically unstable
C
Centrally mediated sympathetic activation leading to a rise of BP and HR
D
Hepatotoxicity
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 9 of 52
The drug of choice in the treatment of myoclonic seizures is:
A
Valproate
B
Phenobarbital
C
Phenytoin
D
Felbamate
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 10 of 52
A client is prescribed phenelzine (Nardil). Which of the following statements by the client should indicate to a nurse that the discharge teaching about this medication has been successful? (Select the one tha does not apply.)
A
“I’ll have to let my surgeon know about this medication before I have my cholecystectomy.â€Â
B
“I guess I will have to give up my glass of red wine with dinner.â€Â
C
“I’ll have to be very careful about reading food and medication labels.â€Â
D
“I’m going to miss my caffeinated coffee in the morning.â€Â
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 11 of 52
Epinephrine produces all of the following effects EXCEPT:
A
Decrease in oxygen consumption
B
Bronchodilation
C
Hyperglycemia
D
Mydriasis
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 12 of 52
Which patient outcomes would be most applicable for the patient who has been taking benzodiazepines? Patient will state:
A
That there are specific foods to avoid while on this medication
B
An understanding of how to increase medication dosage
C
That alcohol is a substance to avoid while on the medication
D
An understanding that he or she can return to work while on this medication
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 13 of 52
Alpha-glucosidase inhibitors act by:
A
Diminishing insulin resistance by increasing glucose uptake and metabolism in muscle and adipose tissues
B
Competitive inhibiting of intestinal alpha-ghucosidases and modulating the postprandial digestion and absorption of starch and disaccharides
C
Reducing the absorption of carbohydrate from the gut
D
Stimulating the beta islet cells of pancreas to produce insulin
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 14 of 52
Indicate the drug, which decreases the craving for alcohol or blunts pleasurable “high†that comes with renewed drinking:
A
Disulfiram
B
Amphetamine
C
Naltrexone
D
Diazepam
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 15 of 52
At admission, the nurse learns that some time ago the client had an infarct in the right motor cortex. During assessment, the nurse would expect to find that:
A
Motor activity on the right side of the body is impaired
B
Motor activity on the left side of the body is impaired
C
The client has impaired reasoning and planning skills
D
The client demonstrated motor aphasia
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 16 of 52
A 57-year-old man with congestive heart failure presents to the emergency department with shortness of breath. He has +2 pitting edema in his extremities as well. A chest X-ray confirms the presence of pulmonary edema. The patient is given intravenous furosemide to diurese the excess fluid. Where in the nephron does furosemide act?
A
Collecting tubule
B
Descending loop of Henle
C
Thick ascending loop of Henle
D
Proximal convoluted tubule
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 17 of 52
Antianxiety agents have:
A
Sedative and hypnotic activity
B
Muscle relaxing and anticonvulsant effects
C
Amnesic properties
D
All of the above
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 18 of 52
Second-order pain is:
A
Sharp,well-localized pain
B
Dull,burning pain
C
Associated with fine myelinated A-delta fibers
D
Effectively reduced by non-narcotic analgesics
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 19 of 52
Action of vitamin D3 is:
A
Increased calcium and phosphate absorption by 1,25-dihydroxyvitamin D3
B
Calcium and phosphate excretion may be decreased by 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3
C
Increased calcium and phosphate resorption by 1,25-dihydroxyvitamin D3; bone formation may be increased by 25,24-dihydroxyvitamin D3
D
All of the above
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 20 of 52
Chronic long-term therapy of myasthenia is usually accomplished with:
A
Edrophonium
B
Neostigmine
C
Echothiophate
D
Carbachol
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 21 of 52
Select an endocrine drug which is a peptide derivative:
A
Oxitocin
B
Prednisolone
C
Nandrolone
D
Progesterone
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 22 of 52
A nurse is planning care for a child who is experiencing depression. Which medication is approved by the U.S. Food and Drug Administration (FDA) for the treatment of depression in children and adolescents?
A
Paroxetine (Paxil)
B
Sertraline (Zoloft)
C
Citalopram (Celexa)
D
Fluoxetine (Prozac)
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 23 of 52
Which of the following fibers is the first to be blocked?
A
Type A alpha fibers
B
B and C fibers
C
Type A beta fibers
D
Type A gamma fibers
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 24 of 52
According to McKim (in “Dependence, addiction, and the self-administration of drugsâ€Â), the ‘priming effect’ of drugs is when:
A
Exposure to a drug that they were previously addicted to can easily trigger a relapse in addiction for abstinent former addicts.
B
Stressful stimuli can trigger a relapse in addiction for abstinent former addicts.
C
Stimuli previously associated with drug delivery (such as drug paraphernalia or a particular drug-using context such as being in a bar) can trigger a relapse in addiction for abstinent former addicts.
D
All of the above.
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 25 of 52
The term ischemic heart disease (IHD) is used to designate all of the following conditions except
A
Angina pectoris
B
Sudden cardiac death
C
Congestive heart failur (CHF)
D
Arrhythmias
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 26 of 52
Which of the following drugs is a potassium channel opener?
A
Pinacidil
B
Hydralazine
C
Glibenclamide
D
Amiloride
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 27 of 52
All of the following drugs demonstrate a fungicidal effect, EXCEPT:
A
Terbinafin
B
Amfotericin B
C
Ketoconazole
D
Myconazol
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 28 of 52
The client has a regular rhythm with a rate of 50. What does this represent?
A
Sinus tachycardia
B
Regular sinus rhythm
C
Sinus bradycardia
D
Frequent PVCs
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 29 of 52
Which of the following agents blocks the chloride channel directly?
A
Secobarbital
B
Flumazenil
C
Zaleplon
D
Picrotoxin
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 30 of 52
Probucol (Lorelco) appears to increase clearance of LDL cholesterol by a non-receptor mediated mechanism. This consideration is:
A
TRUE
B
FALSE
C
All
D
None
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 31 of 52
An 83-year-old man has been effectively treated with hydrochlorothiazide to control his elevated blood pressure. He has had a recent onset of weakness. Blood chemistry analysis reveals hypokalemia. Another drug is added, and 1 month later his serum K+ is normal. Which of the following drugs most likely helped normalize his serum potassium levels?
A
Acetazolamice
B
Amiloride
C
Furosemide
D
Metolazone
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 32 of 52
A 22-year-old nursing student has been taking NoDoz (caffeine) tablets for the past few weeks to 'make it through' the end of the semester and exam week. She is in the university clinic today because she is 'exhausted.' What nursing diagnosis may be appropriate for her?
A
Noncompliance
B
Impaired physical mobility
C
Sleep deprivation
D
Imbalanced nutrition: less than body requirements
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 33 of 52
Which of the following neuromuscular blocking drugs is an intermediate-duration muscle relaxant?
A
Vecuronium
B
Tubocurarine
C
Pancuronium
D
Rapacuronium
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 34 of 52
Serious side effects of glucocorticoids include the following, EXCEPT:
A
Acute peptic ulcers
B
Iatrogenic Cushing’s syndrome (rounding, puffiness, fat deposition and plethora alter the appearance of the face – moon faces)
C
Salicylism (vomiting, tinnitus, decreased hearing, and vertigo)
D
Hypomania or acute psychosis
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 35 of 52
Which of the following statements concerning vitamin B12 (cyanocobalamin) functions are true:
A
Active functional form is pyridoxal phosphate, which is an essential coenzyme for transamination and decarboxylation of amino acids in more than 50 different enzyme systems
B
Essential constituent of coenzyme A, the important coenzyme for acyl transfer in the TCA cycle and de novo fatty acid synthesis
C
Coenzyme for numerous metabolic reaction, including transformation of methylamlonyl CoA to succinyl CoA in the metabolism of propionate; DNA synthesis (acts in concert with folic acid); transmethylation e.g. methionine synthesis from homocysteine
D
An extremely important antioxidant, which protects cell membrane lipids from peroxidation by breaking the chain reaction of free radical formation to which polyunsaturated fatty acids are particularly vulnerable
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 36 of 52
Irreversible interaction of an antagonist with a receptor is due to:
A
Ionic bonds
B
Hydrogen bonds
C
Covalent bonds
D
All of the above
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 37 of 52
When a patient is receiving diuretic therapy, which of these assessment measures would best reflect the patient’s fluid volume status?
A
Blood pressure and pulse
B
Serum potassium and sodium levels
C
Intake, output, and daily weight
D
Measurements of abdominal girth and calf circumference
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 38 of 52
The client is taking an ACE inhibitor. What is a contraindication to taking this drug?
A
Hypertension
B
Bronchospasm
C
Renal artery stenosis
D
Heart failure
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 39 of 52
Choose the drug which is a H2-receptor antagonist:
A
Omeprazole
B
Pirenzepine
C
Carbenoxolone
D
Ranitidine
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 40 of 52
All of the following antimalarial drugs influence blood schizonts, EXCEPT:
A
Mefloquine
B
Chloroquine
C
Primaquine
D
Quinidine
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 41 of 52
Subtype-selective alfa1 receptor antagonists such as tamsulosin terazosin alfusosin are efficacious in:
A
Hyperthyroidism
B
Cardiac arrhythmias
C
Benign prostatic hyperplasia (BPH)
D
Asthma
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 42 of 52
Drugs useful in treatment of hypertension include the following EXCEPT:
A
Nifedipine
B
Methysergide
C
Methyldopa
D
Hydralazine
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 43 of 52
What does “pharmacokinetics†include?
A
Localization of drug action
B
Mechanisms of drug action
C
Excretion of substances
D
Interaction of substances
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 44 of 52
General principles of anti-infective therapy are:
A
Clinical judgment of microbiological factors
B
Definitive identification of a bacterial infection and the microorganism’s susceptibility
C
Optimal route of administration, dose, dosing frequency and duration of treatment
D
All of the above
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 45 of 52
Which of the following CNS stimulants are the agents of selective effect?
A
Analeptics
B
General tonics
C
Psychostimulants
D
Actoprotectors
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 46 of 52
This drug blocks alpha-1 adrenergic receptors:
A
Prazosin
B
Clonidine
C
Enalapril
D
Nifedipine
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 47 of 52
A 58-year-old male with diabetes comes to the clinic complaining of difficulty achieving an erection. He has a history of cardiovascular disease. The physician recommends sildenafil. What is the mechanism of action of this agent?
A
Increasing intracellular cAMP
B
Parasympathetic stimulation
C
Sympathetic stimulation
D
Vasodilation
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 48 of 52
A 55-year-old woman with a long history of poorly controlled essential hypertension had recently added atenolol to her therapeutic regimen. Which of the following was most likely a primary mechanism that mediated the antihypertensive effect of atenolol in this patient?
A
Dilation of large veins
B
Inhibition of epinephrine release from the adrenal medulla
C
Nitroprusside
D
Fenoldopam
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 49 of 52
A patient has been taking digoxin at home but took an accidental overdose and has developed toxicity. The patient has been admitted to the telemetry unit, where the physician has ordered digoxin immune Fab (Digifab). The patient asks the nurse why the medication is ordered. What is the nurse’s best response?
A
It will increase your heart rate.
B
This drug helps to lower your potassium levels.
C
It helps to convert the irregular heart rhythm to a more normal rhythm.
D
This drug is an antidote to digoxin and will help to lower the blood levels.
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 50 of 52
Which medication would the nurse expect to administer when observing that a patient is fidgety, demonstrates motor restlessness, and jiggles both legs when asked to sit down?
A
Olanzapine (Zyprexa)
B
Molindone (Moban)
C
Biperiden (Akineton)
D
Thioridazine (Mellaril)
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 51 of 52
select the odd one: Beta-adrenoceptor antagonists:
A
Are indicated in patients with stable heart failure
B
Prolong life in survivors of myocardial infarction
C
Improve performance of sprinters
D
The antihypertensive effect is antagonized by non-steroidal anti-inflammatory drugs (NSAIDs)
Select an option. Use Strike to cross one out.
HESI LPN · HESI Cardiovascular Drugs Pharmacology NCLEX Questions
Question 52 of 52
Action mechanism of alkylating agents is:
A
Producing carbonium ions altering protein structure
B
Producing carbonium ions altering DNA structure
C
Structural antagonism against purine and pyrimidine
D
Inhibition of DNA-dependent RNA synthesis
Select an option. Use Strike to cross one out.
