Which of the following reactions is considered to be in the category of phase II drug metabolism?
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Question 2 of 106
Most drug receptors are
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Question 3 of 106
A nursing instructor is preparing a teaching plan for a group of nursing students about pharmacology. When describing this topic, the instructor would focus the discussion on which of the following as an essential aspect?
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Question 4 of 106
A student nurse asks a nursing instructor how to remember all of the antibiotic drugs since there are so many. What is the best response by the nursing instructor?
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Question 5 of 106
The term polypharmacy is:
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Question 6 of 106
An 18-year-old man is scheduled to have four wisdom teeth removed. The procedure is done under general anesthetic and there are no postoperative complications. He is discharged home with a prescription for codeine for pain control. Three days later, he contacts his physician and complains of difficulty moving his bowels. This type of adverse drug reaction is most similar to which of the following?
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Question 7 of 106
The following infections have been paired with appropriate antibacterial therapy:
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Question 8 of 106
Which LDL-C-lowering drug class includes three yearly administrations via subcutaneous injection?
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Question 9 of 106
Two drugs that are found to be chemically equivalent, but not biologically equivalent or therapeutically equivalent are said to differ in
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Question 10 of 106
Can be calculated by dividing rate of elimination by drug concentration
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Question 11 of 106
Which of the following terms best describes a drug that blocks the action of epinephrine at its receptors by occupying those receptors without activating them?
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Question 12 of 106
What is the most reliable method to calculate a pediatric patient's medication dosage?
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Question 13 of 106
Which of the following statements is (are) true concerning passage across body membranes?
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Question 14 of 106
If an agonist can produce maximal effects and has high efficacy its called:
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Question 15 of 106
Acidic drugs mainly bind to plasma
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Question 16 of 106
All the following result in constipation except:
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Question 17 of 106
Which of the following statements concerning a drug receptor is true?
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Question 18 of 106
The following are subject to extensive presystemic (first-pass) metabolism:
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Question 19 of 106
Which of the following is the shortest acting antiarrhythmic drug?
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Question 20 of 106
Isoniazid:
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Question 21 of 106
Cross MATCH each drug to its specific feature in management of diarrhea: Pectin & kaolin
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Question 22 of 106
Which of the following drugs is known to have teratogenic effects?
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Question 23 of 106
The following infections have been paired with appropriate drug therapy:
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Question 24 of 106
Adverse effects associated with the interferons include:
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Question 25 of 106
Voriconazole:
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Question 26 of 106
A patient receives a single dose of antibiotics following a prostate needle biopsy. He takes $500 \mathrm{mg}$ of ciprofloxacin immediately after completion of the procedure. The half-life of the medication is $8 \mathrm{~h}$. At approximately how many half-lives will it take for $90 \%$ of the drug to be excreted from the body?
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Question 27 of 106
What is the primary benefit of beta-blockers in heart failure?
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Question 28 of 106
In comparing two drugs, the dose-response curve for the drug that is more efficacious would
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Question 29 of 106
The nurse is preparing to administer a medication from a multidose bottle. The label is torn and soiled but the name of the medication is still readable. What is the nurse's priority action?
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Question 30 of 106
Conscious sedation may be induced by
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Question 31 of 106
The 'dominant lethal' test involves the treatment of a male adult animal with a chemical before mating; the pregnant female is later examined for fetal death and abnormalities. The dominant lethal test therefore is a test of
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Question 32 of 106
Which of the following is a Schedule II controlled substance?
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Question 33 of 106
In the case of an intramuscular injection of a drug:
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Question 34 of 106
Inclisiran works by:
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Question 35 of 106
During cisplatin therapy:
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Question 36 of 106
The initial distribution of a drug into tissue is determined chiefly by the
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Question 37 of 106
Fibrates primarily reduce which of the following?
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Question 38 of 106
If one dose of a drug is administered and the drug's half-life in the body is 3 hours, what percentage of the drug would be left after four half-lives?
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Question 39 of 106
True statement (s) concerning misoprostol include all the following except:
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Question 40 of 106
In the fusion method of making cocoa butter suppositories, which substance is most likely to be used to lubricate the mold?
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Question 41 of 106
A 16-year-old male high school football player takes $800 \mathrm{mg}$ of ibuprofen after morning practice for a sore knee. Ibuprofen has a half-life of about $2 \mathrm{~h}$. What percentage of the original plasma load of ibuprofen will remain in his blood when afternoon practice starts in $4 \mathrm{~h}$ ?
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Question 42 of 106
Disadvantages of tricyclic antidepressants include:
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Question 43 of 106
The FDA established a safety information and adverse events reporting program called MedWatch. Which individuals can access the MedWatch website to obtain safety alerts on drugs, devices, or dietary supplements?
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Question 44 of 106
FDA-approved in November 2019, voxelotor is used to treat which of these conditions?
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Question 45 of 106
The apparent volume of distribution:
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Question 46 of 106
A group of nursing students are reviewing information about drug development in the United States in preparation for an exam. The students demonstrate understanding of this material when they identify testing of which of the following as one of the first steps?
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Question 47 of 106
Neuropathic pain may be managed by
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Question 48 of 106
A 66-year-old woman with chronic bronchitis who has smoked two packs of cigarettes per day for 50 years would like to quit. She has tried to quit five times in the past but felt she could not go long without a cigarette. The nicotine in her cigarettes stimulates many cells in her body by binding certain receptors. Which describes the response when nicotine binds its target receptor?
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Question 49 of 106
The LPN is collecting objective data for inclusion in the nursing assessment. Which piece of information indicates that the LPN has a clear understanding of objective assessment data?
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Question 50 of 106
A ceramic mortar may be preferable to a glass mortar when
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Question 51 of 106
Clearance is useful in calculation of
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Question 52 of 106
What government agency or agencies control(s) prescription or legend medications?
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Question 53 of 106
Regarding 'first-order kinetics', the following is Wrong:
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Question 54 of 106
The following concerning the use of benzodiazepines is not true :
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Question 55 of 106
All these drugs are classified as SSRIs, except which?
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Question 56 of 106
Which of these tetracyclines is used in the treatment of hyponatremia due to SIADH?
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Question 57 of 106
Monitoring plasma/serum drug concentrations of the following drugs is recognized as a valuable supplement to clinical monitoring:
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Question 58 of 106
All of the following carbohydrates are considered to be polysaccharides except
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Question 59 of 106
The FDA regulates the following areas concerning drugs:
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Question 60 of 106
A physician has ordered intramuscular (IM) injections of morphine, a narcotic, every 4 hours as needed for pain in a motor vehicle accident victim. The nurse is aware this drug has a high abuse potential. Under what category would morphine be classified?
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Question 61 of 106
Which of the following drugs is/are decomposed by gastric acidity?
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Question 62 of 106
Which of the following drugs is considered to be the agent of choice for anaphylactic reactions?
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Question 63 of 106
Which drug is contraindicated in patients with second or third-degree atrioventricular heart block?
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Question 64 of 106
Which of the following statements about aspirin is INCORRECT:
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Question 65 of 106
If controlled substances are administered but not dispensed in a physician's office, the medical record may be used as the documentation of the use of the controlled substance.
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Question 66 of 106
The following drugs do not readily cross to the CNS
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Question 67 of 106
In vomiting induced by cancer chemotherapy, the following is least likely used
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Question 68 of 106
Antihyperlipidemic drug most likely to reduce serum digoxin levels, serum vancomycin levels, and thiazide levels:
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Question 69 of 106
A patient is receiving digoxin as treatment for heart failure. Which of the following would be most important for the nurse to monitor to reduce the risk for toxicity?
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Question 70 of 106
Which drug can cause hypothyroidism or hyperthyroidism due to its iodine content?
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Question 71 of 106
The following drugs exert their principal effects by enzyme inhibition:
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Question 72 of 106
Which of the following is located in the body of the prescription?
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Question 73 of 106
Which one of the following statements regarding NSAIDs is FALSE?
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Question 74 of 106
Drug dependence is always unethical.
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Question 75 of 106
Which of these immunosuppressant drugs works as an mTOR inhibitor?
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Question 76 of 106
The following oral drugs do not require absorption from the gut to exert a therapeutic effect:
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Question 77 of 106
The nurse is caring for a patient who is taking warfarin. The nurse notes the presence of gross hematuria and large areas of bruising on the patient's body. The nurse notifies the health care prescriber and anticipates what medication will be ordered?
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Question 78 of 106
The patient is prescribed a medication that was just placed in Phase IV study. The patient tells the nurse, 'This medication is too expensive. Could the doctor order a generic form of this medication?' What is the nurse's most accurate response?
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Question 79 of 106
A 31-year-old man is brought to the emergency department complaining of dyspnea. He has a history of asthma and has had multiple asthma attacks requiring intubation for airway maintenance. He is noncompliant with his medications prescribed for this condition. Physical examination reveals a young man in acute distress. His room air oxygen saturation is $87 \%$. In addition to administration of oxygen, immediate drug administration of albuterol should be administered by which of the following routes?
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Question 80 of 106
Ezetimibe primarily reduces which lipoprotein?
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Question 81 of 106
Gentamicin, an aminoglycoside:
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Question 82 of 106
Chronic use of which of the following may increase paracetamol toxicity
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Question 83 of 106
The earliest evidence that a drug is stored in tissue is
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Question 84 of 106
The following is not true concerning tricyclic antidepressant toxicity:
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Question 85 of 106
Cross MATCH each drug to its specific adverse effect: Senna
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Question 86 of 106
Pyridoxine is an effective antidote for which of the following drugs?
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Question 87 of 106
Compulsive gambling, hypersexuality, and over-eating are unusual side effects associated with which of these drugs?
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Question 88 of 106
A nurse is reviewing key events in the history of pharmacology with a student nurse. Which student comment from below indicates a need for further teaching?
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Question 89 of 106
Which drug can cause ventricular tachycardia in the presence of ischemic heart disease?
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Question 90 of 106
Which one of the following drugs decreases cholesterol synthesis by inhibiting the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase?
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Question 91 of 106
What is the common mechanism of action of all the Class 1 Antiarrhythmic drugs?
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Question 92 of 106
Parenteral administration:
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Question 93 of 106
Persistent dry cough and hyperkalemia are side effects associated with which of these drug classes?
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Question 94 of 106
OTC drugs are not regulated by the FDA.
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Question 95 of 106
The nurse determines that a prescribed medication has not been administered as ordered on the previous shift. What action will the nurse take?
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Question 96 of 106
The telephone triage nurse receives a call from a patient asking for a prescription for a narcotic to manage his surgical pain. The nurse explains that narcotic prescriptions must be written and cannot be called in to the pharmacy. The patient says, 'Why are narcotics so difficult to get a prescription for?' What is the nurse's best response?
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Question 97 of 106
Bacteria that grow at temperatures as high as 55°C are known as
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Question 98 of 106
Which class of drugs is considered first-line therapy for chronic heart failure?
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Question 99 of 106
Regarding termination of drug action
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Question 100 of 106
Which organ is involved in the first-pass effect after oral administration of a drug?
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Question 101 of 106
A drug that binds to a receptor and produces a biological response that mimics the response to the endogenous ligand is known as
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Question 102 of 106
The fact that the consumer will receive the same standard of medication with each prescription
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Question 103 of 106
Which of the following anti-arrhythmic drug decreases the action potential duration in Purkinje fibers?
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Question 104 of 106
After teaching a group of nursing students about nonprescription drugs, the nursing instructor determines that the teaching was successful when the students identify which of the following?
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Question 105 of 106
Which equation is used to predict the stability of a drug product at room temperature from experiments at accelerated temperature?
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Question 106 of 106
Which of the following is the primary mechanism of action of statins?
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