HESI Basic pharmacology principles

HESI LPN · HESI Basic pharmacology principles

Question 1 of 103

Sodium bicarbonate has the following disadvantages except:

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HESI LPN · HESI Basic pharmacology principles

Question 2 of 103

Used to describe drugs with identical areas under the curve (AUCs)

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HESI LPN · HESI Basic pharmacology principles

Question 3 of 103

Nonionic surface-active agents used as synthetic emulsifiers include

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HESI LPN · HESI Basic pharmacology principles

Question 4 of 103

The following antiemetic is incorrectly matched to its mechanism of action?

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HESI LPN · HESI Basic pharmacology principles

Question 5 of 103

The following inhibit at least one of the hepatic CYP450 isoenzymes:

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HESI LPN · HESI Basic pharmacology principles

Question 6 of 103

The treatment of hyperlipidemic patients with nicotinic acid (niacin) results in:

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HESI LPN · HESI Basic pharmacology principles

Question 7 of 103

Which action will the nurse take if a dosage is unclear on a healthcare provider's order?

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HESI LPN · HESI Basic pharmacology principles

Question 8 of 103

Which of the following is not a NSAID? :

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HESI LPN · HESI Basic pharmacology principles

Question 9 of 103

The following drugs exert their effects by binding to receptors and mimicking the effects of the endogenous ligand (i.e. are agonists):

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HESI LPN · HESI Basic pharmacology principles

Question 10 of 103

All of the following choices are true with regard to cytochrome P-450 hepatic microsomal enzymes except that they

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HESI LPN · HESI Basic pharmacology principles

Question 11 of 103

CD4+T cells specifically recognize antigens in which form?

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HESI LPN · HESI Basic pharmacology principles

Question 12 of 103

While studying for the test, the nursing student encounters the following drug: papaverine (Pavabid). What does the nursing student identify the name Pavabid as?

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HESI LPN · HESI Basic pharmacology principles

Question 13 of 103

Ulcerative stomatitis, pulmonary fibrosis, and hepatotoxicity are notable side effects of which of these drugs?

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HESI LPN · HESI Basic pharmacology principles

Question 14 of 103

The LPN/VN is assessing a patient before giving a drug for blood pressure management. The nurse notes the blood pressure to be 90/50 mm Hg. What is the nurse's best action?

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HESI LPN · HESI Basic pharmacology principles

Question 15 of 103

A hospitalized patient with systemic infection is receiving intravenous antibiotics. He also has hepatic and renal insufficiency. After receiving medications for 5 days, he is found by nursing staff to be jaundiced. Drug toxicology profile is obtained and indicated drug levels of 10 times the acceptable value. Which of the following drug administration schemes is most likely to explain this situation?

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HESI LPN · HESI Basic pharmacology principles

Question 16 of 103

A nurse is explaining the benefits of using a prototype approach to learn pharmacology to a nursing student. The nurse understands that studying the prototype drug makes it possible to predict certain characteristics of drugs in the same class. Which response by the nursing student below indicates the need for further teaching?

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HESI LPN · HESI Basic pharmacology principles

Question 17 of 103

Which one of the following drugs binds bile acids in the intestine, thus preventing their return to the liver via the enterohepatic circulation?

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HESI LPN · HESI Basic pharmacology principles

Question 18 of 103

Animal testing of potential new therapeutic agents

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HESI LPN · HESI Basic pharmacology principles

Question 19 of 103

is expressed in both the intestinal epithelium and the kidney.

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HESI LPN · HESI Basic pharmacology principles

Question 20 of 103

Cross MATCH each drug to its specific feature in management of diarrhea: Bismuth subsalicylate

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HESI LPN · HESI Basic pharmacology principles

Question 21 of 103

Which of the following definition (s) is (are) incorrect

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HESI LPN · HESI Basic pharmacology principles

Question 22 of 103

The following can reduce GFR:

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HESI LPN · HESI Basic pharmacology principles

Question 23 of 103

Drug/s reducing hepatic 1st pass metabolism is/are:

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HESI LPN · HESI Basic pharmacology principles

Question 24 of 103

The government agency that regulates the development of drugs is the

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HESI LPN · HESI Basic pharmacology principles

Question 25 of 103

The following antibacterial drugs inhibit folic acid biosynthesis:

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HESI LPN · HESI Basic pharmacology principles

Question 26 of 103

A 19-year-old female has a history of absence seizures. She currently takes ethosuximide to control her symptoms. The process of eliminating this drug involves multiple steps of metabolism followed by excretion. Many organs take part in both metabolism as well as excretion of drugs. Which of the following describes a step of metabolism?

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HESI LPN · HESI Basic pharmacology principles

Question 27 of 103

Cross MATCH each drug to its specific adverse effect: Paraffin oil

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HESI LPN · HESI Basic pharmacology principles

Question 28 of 103

A client is receiving a very expensive medication. The client asks the nurse why the medicine is so expensive. What is the best response by the nurse?

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HESI LPN · HESI Basic pharmacology principles

Question 29 of 103

Which drug can cause thyroid dysfunction?

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HESI LPN · HESI Basic pharmacology principles

Question 30 of 103

Which of the following is true concerning generic and trade names of drugs?

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HESI LPN · HESI Basic pharmacology principles

Question 31 of 103

A nurse working in radiology administers iodine to a patient who is having a computed tomography (CT) scan. The nurse working on the oncology unit administers chemotherapy to patients who have cancer. At the Public Health Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to a 14-month-old child as a routine immunization. Which branch of pharmacology best describes the actions of all three nurses?

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HESI LPN · HESI Basic pharmacology principles

Question 32 of 103

The term therapeutic window refers to:

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HESI LPN · HESI Basic pharmacology principles

Question 33 of 103

The nurse is helping a client review a prescription from the health care provider. When examining the prescription, which of the following would the nurse expect to find documented?

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HESI LPN · HESI Basic pharmacology principles

Question 34 of 103

The medical assistant should allow the drug sales representative to leave any medication that might be used in the office for patient care.

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HESI LPN · HESI Basic pharmacology principles

Question 35 of 103

A common side effect of volanesorsen is:

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HESI LPN · HESI Basic pharmacology principles

Question 36 of 103

Which of the following would the nurse identify as a factor that alters drug response in children and infants?

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HESI LPN · HESI Basic pharmacology principles

Question 37 of 103

Mesna is used to reduce the risk of hemorrhagic cystitis from which drug?

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HESI LPN · HESI Basic pharmacology principles

Question 38 of 103

The following are examples of prodrugs:

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HESI LPN · HESI Basic pharmacology principles

Question 39 of 103

Which of the following statements describes plasmids? They

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HESI LPN · HESI Basic pharmacology principles

Question 40 of 103

The following drugs may be administered transcutaneously to produce their systemic therapeutic effect:

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HESI LPN · HESI Basic pharmacology principles

Question 41 of 103

Which of the following antiarrhythmic drug is indicated to control heart rate in SVT or A fib, especially with congestive heart failure?

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HESI LPN · HESI Basic pharmacology principles

Question 42 of 103

Extraction ratio (E) of a drug is

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HESI LPN · HESI Basic pharmacology principles

Question 43 of 103

Creatinine clearance is used as a measurement of

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HESI LPN · HESI Basic pharmacology principles

Question 44 of 103

Which of the following is not a subject of pharmacokinetics?

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HESI LPN · HESI Basic pharmacology principles

Question 45 of 103

Rectal suppositories intended for adult use usually weigh approximately

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HESI LPN · HESI Basic pharmacology principles

Question 46 of 103

Which drug is used to treat heart failure and can cause vision changes (xanthopsia)?

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HESI LPN · HESI Basic pharmacology principles

Question 47 of 103

A patient in the clinic reports difficulty tolerating the current ACE inhibitor medication, and questions if another medication could be used. The nurse correctly suspects the prescriber will choose which medication, which affects the renin-angiotensin-aldosterone system?

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HESI LPN · HESI Basic pharmacology principles

Question 48 of 103

Which drug can cause liver damage due to its long half-life?

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HESI LPN · HESI Basic pharmacology principles

Question 49 of 103

The following are used in the prophylaxis or treatment of influenza:

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HESI LPN · HESI Basic pharmacology principles

Question 50 of 103

Which drug is a potassium-sparing diuretic used in heart failure management?

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HESI LPN · HESI Basic pharmacology principles

Question 51 of 103

Drug standards are the same in all states and countries.

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HESI LPN · HESI Basic pharmacology principles

Question 52 of 103

Which mechanism is most often responsible for chemical degradation?

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HESI LPN · HESI Basic pharmacology principles

Question 53 of 103

Neuroleptanalgesia may be induced by

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HESI LPN · HESI Basic pharmacology principles

Question 54 of 103

Which of the following statements is correct?

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HESI LPN · HESI Basic pharmacology principles

Question 55 of 103

The following adverse effects are paired with the correct causative antimalarial drug:

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HESI LPN · HESI Basic pharmacology principles

Question 56 of 103

The standard that specifies the type and concentration of a substance in a drug

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HESI LPN · HESI Basic pharmacology principles

Question 57 of 103

Pretreatment with propranolol will block which one of the following?

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HESI LPN · HESI Basic pharmacology principles

Question 58 of 103

For a drug that obeys first-order (linear) kinetics and fits a one-compartment model for elimination:

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HESI LPN · HESI Basic pharmacology principles

Question 59 of 103

True statement concerning sucralfate

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HESI LPN · HESI Basic pharmacology principles

Question 60 of 103

The dose of benzodiazepines should be adjusted in:

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HESI LPN · HESI Basic pharmacology principles

Question 61 of 103

The following cytotoxic drugs are paired with a characteristic adverse effect:

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HESI LPN · HESI Basic pharmacology principles

Question 62 of 103

A nurse is reading a journal article about seasonal allergies and comes across the name of the drug loratadine. The nurse identifies this drug name as which of the following?

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HESI LPN · HESI Basic pharmacology principles

Question 63 of 103

A drug is defined as a biologically active substance that can modify

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HESI LPN · HESI Basic pharmacology principles

Question 64 of 103

Which of these drugs should be avoided 48-hours before/after use of IV contrast media?

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HESI LPN · HESI Basic pharmacology principles

Question 65 of 103

An inventory of controlled substances must be taken in a physician's office every 5 years.

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HESI LPN · HESI Basic pharmacology principles

Question 66 of 103

The heading of a prescription contains the following information except the

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HESI LPN · HESI Basic pharmacology principles

Question 67 of 103

What is benzyl benzoate?

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HESI LPN · HESI Basic pharmacology principles

Question 68 of 103

Which of these drugs works by targeting the auxiliary ÃƒÅ½Ã‚Â±2ÃƒÅ½Ã‚Â´ subunit of voltage-dependent calcium channels?

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HESI LPN · HESI Basic pharmacology principles

Question 69 of 103

An antidepressant useful for smoking cessation is:

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HESI LPN · HESI Basic pharmacology principles

Question 70 of 103

What would be the best source of drug information for a nurse?

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HESI LPN · HESI Basic pharmacology principles

Question 71 of 103

A medical student is doing a summer research project studying five antibiotics to determine potency using the EC50. Antibiotics are placed in plated culture wells with 100,000 CFU of Escherichia coli. The EC50 results for the five antibiotics are shown in the following choices. Based on the results, the most potent antibiotic is

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HESI LPN · HESI Basic pharmacology principles

Question 72 of 103

Cefuroxime:

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Question 73 of 103

Which one of the following drugs causes a decrease in liver triglyceride synthesis by limiting available free fatty acids needed as building blocks for this pathway?

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HESI LPN · HESI Basic pharmacology principles

Question 74 of 103

This drug decreases blood levels of high-density lipoproteins (HDL):

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HESI LPN · HESI Basic pharmacology principles

Question 75 of 103

A 28-year-old man with seborrheic dermatitis is prescribed a topical corticosteroid crÃƒÆ’Ã‚Â¨me by his dermatologist in hopes of alleviating the chronic rash and erythema on the cheeks. Which of the following steps is most critical to achieve a therapeutic drug concentration in plasma?

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HESI LPN · HESI Basic pharmacology principles

Question 76 of 103

The excretion of a weakly acidic drug generally is more rapid in alkaline urine than in acidic urine. This process occurs because

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HESI LPN · HESI Basic pharmacology principles

Question 77 of 103

The patient tells the nurse about a new drug being tested to treat the disease she was diagnosed with and asks the nurse whether the doctor can prescribe a medication still in the preclinical phase of testing. What is the nurse's best response?

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HESI LPN · HESI Basic pharmacology principles

Question 78 of 103

Which of the following drugs is used as a Class II antiarrhythmic agent and works by increasing vagal tone?

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HESI LPN · HESI Basic pharmacology principles

Question 79 of 103

A nurse is providing medication education to a client with hypertension. The nurse teaches the client that the healthcare provider ordered a diuretic to decrease the amount of fluid in the client's body. Which statement best describes the nurse's instruction?

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HESI LPN · HESI Basic pharmacology principles

Question 80 of 103

A 15-year-old boy who has diabetes and is insulin dependent is brought to the emergency department after collapsing at a baseball game. His blood sugar is $463 \mathrm{mg} / \mathrm{dL}$ by finger stick. Which of the following routes of administration would be most efficacious for medications to bring the blood sugar down?

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HESI LPN · HESI Basic pharmacology principles

Question 81 of 103

A 21-year-old man presents to his primary care physician complaining of a single, painless ulcer on his penis, which he first noticed a few days ago. He admits to multiple sexual partners. You want to treat him for syphilis with penicillin G, but his history includes an itchy rash following amoxicillin treatment as a child. What must first occur in the body for a penicillin to become allergenic?

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HESI LPN · HESI Basic pharmacology principles

Question 82 of 103

If the plasma concentration of a drug declines with 'first-order kinetics', this means that

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HESI LPN · HESI Basic pharmacology principles

Question 83 of 103

The nurse observes that after administration of a drug the patient has developed itching and a skin rash. The nurse interprets these findings as which of the following?

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HESI LPN · HESI Basic pharmacology principles

Question 84 of 103

The nurse transcribes an order to administer Valium 10 mg IV stat. This order is correctly interpreted by the nurse to mean it should be provided how?

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HESI LPN · HESI Basic pharmacology principles

Question 85 of 103

The route of drug administration that gives the most rapid onset of the pharmacological effect is

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HESI LPN · HESI Basic pharmacology principles

Question 86 of 103

Cross Match each of the following adverse effect to the corresponding drug: Hyperuricemia & bleeding

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HESI LPN · HESI Basic pharmacology principles

Question 87 of 103

Glucose is a carbohydrate that cannot be hydrolyzed into a simpler substance. It is best described as

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HESI LPN · HESI Basic pharmacology principles

Question 88 of 103

What does pharmacokinetics include?

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HESI LPN · HESI Basic pharmacology principles

Question 89 of 103

Which example best demonstrates safe drug administration by the nurse?

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HESI LPN · HESI Basic pharmacology principles

Question 90 of 103

The following drug is NOT correctly matched to its side effects

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HESI LPN · HESI Basic pharmacology principles

Question 91 of 103

Which drug is known to cause a feeling of warmth and redness of the face?

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HESI LPN · HESI Basic pharmacology principles

Question 92 of 103

Ezetimibe is often combined with which class of drugs for a synergistic effect?

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HESI LPN · HESI Basic pharmacology principles

Question 93 of 103

A teratogenic action is:

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HESI LPN · HESI Basic pharmacology principles

Question 94 of 103

The following antifungal agents have been paired correctly with an appropriate indication:

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HESI LPN · HESI Basic pharmacology principles

Question 95 of 103

Advantages of oral administration of a drug include all the following except

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HESI LPN · HESI Basic pharmacology principles

Question 96 of 103

The formulary for medications is approved by the

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HESI LPN · HESI Basic pharmacology principles

Question 97 of 103

Reduction in sexual function is least seen with

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HESI LPN · HESI Basic pharmacology principles

Question 98 of 103

Niacin inhibits which enzyme in adipose tissue?

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HESI LPN · HESI Basic pharmacology principles

Question 99 of 103

Ciprofloxacin:

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Question 100 of 103

The following is not common between pethidine & tramadol:

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Question 101 of 103

Which of the following terms best describes an antagonist that interacts directly with the agonist and not at all or only incidentally, with the receptor?

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Question 102 of 103

Which priority assessment must you make before giving any patient a drug by mouth?

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Question 103 of 103

A patient has an order for metoprolol. Prior to medication administration, what does the nurse need to assess?

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