Pediatric Immunizations NCLEX Questions

ATI RN · Pediatric Immunizations NCLEX Questions

Question 1 of 57

Which of the following is NOT a structural chain in class I MHC?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 2 of 57

A 3-year-old boy presented with recurrent subcutaneous abscesses, lymphadenitis, osteomyelitis, and family history of recurrent infections. The hallmark of this condition is

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 3 of 57

Repeated meningococcal infections suggest what type of immune disorder?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 4 of 57

Graft vs host disease often accompanies transplantation of?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 5 of 57

Which of the following is required for a CD8+ cell to differentiate into an effector cytotoxic T cell (CTL)? Is this a physical interaction?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 6 of 57

Which one of the following cytokines plays the most important role in protection against intracellular growth (reactivation) of Mycobacterium tuberculosis?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 7 of 57

is frequently found on the surface of B cells co-expressed with These two classes are co-expressed not by class switching but by alternative processing of a primary RNA transcript. Both molecules expressed on the single mature B cell have the same binding specificity for antigen.

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 8 of 57

How many doses of the Hepatitis B vaccine (5 Î¼g HBsAg in 0.5 mL intramuscular) are required to reach a protective level of antibody?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 9 of 57

long statements about Kidney transplant that has been rejected within minutes, choose the wrong statement

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 10 of 57

Cortex

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 11 of 57

Which of the following is the correct order for a lymphocyte to be activated?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 12 of 57

Defects in Macrophage to kill bacteria that synthesis Catalase; this called?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 13 of 57

The membrane attack complex (MAC) uses C3 to activate the final part of the complement pathway. It is important in defense against Neisseria. Which of the following components is/are inserted into the plasma membrane of the target cell, allowing for free passage of water/solute and thus killing the cell?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 14 of 57

Somatic hypermutation in the Immunoglobulin (Ig) variable region occurs...?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 15 of 57

Matching: Complement deficiency - Recurrent neisserial infection

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 16 of 57

The earliest clinical feature of ataxia-telangiectasia is

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 17 of 57

If a virus snuck into the body, which of the following would you expect to be the last killer?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 18 of 57

Recognize antigens bound to MHC

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 19 of 57

Matching: Immunodeficiency - High frequency of autoimmune disorders

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 20 of 57

The invariant chain the empty peptide-binding groove. After vesicle fusion, the invariant chain is and peptides can enter the MHC class II grove.

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 21 of 57

A child presents with recurrent infections with bacteria, fungi, and viruses. The resident asks the attending physician about IL-2R gamma chain mutations, as the patient is a male. The attending physician makes a diagnosis and begins writing orders for bone marrow transplantation and possible gene therapy. Which of the following does the patient have?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 22 of 57

Natural killer cell receptors NKG2/CD94 and killer inhibitory receptors allow for the killing of antibodies in the presence of:

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 23 of 57

Which of the following is a soluble pattern recognition receptor

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 24 of 57

Where are single-positive (SP) cells found?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 25 of 57

What surface immunoglobulins are present once an immature B cell becomes a mature (peripheral) B cell?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 26 of 57

When we inhibit alternative pathway convertase, all of the following would decrease EXCEPT

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 27 of 57

The T-cell antigenic receptor

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 28 of 57

An 8-month-old infant presented with chronic diarrhea, persistent right ear discharge, oral candidiasis responding poorly to antifungal drugs, and failure to thrive. On examination the infant has exfoliative erythroderma, lymphadenopathy, and hepatosplenomegaly. Peripheral blood showed eosinophilia and elevated IgE. The parents are young first cousin and he is their first baby. Of the following, the MOST likely diagnosis is

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 29 of 57

Which of the following is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 30 of 57

Which of the following is used extensively to detect antigens in cells or tissue sections, as well as to screen for auto-antibodies to cell or tissue antigens?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 31 of 57

Which of the following are pluripotential, self-renewing CD34+ cells?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 32 of 57

Granulocyte colony-stimulating factor (G-CSF) causes an increase in the production of which of the following in the bone marrow?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 33 of 57

Which of the following are located in chromosome 7 within human T-cell receptors?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 34 of 57

Recurrent infections with neutropenia are a distinctive feature of

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 35 of 57

A 4-year-old child has atopic dermatitis due to severe allergies to dust, animal dander, and many kinds of pollens. Mediators released from which cell type are responsible for the clinical manifestations immediately following exposure to these substances?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 36 of 57

CD4+ cells recognize antigen displayed on ___ MHC molecules and CD8+ cells recognize antigen displayed on ___ MHC molecules. ___ has TH1 and TH2 cell populations.

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 37 of 57

Increases marrow production of neutrophils

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 38 of 57

During B cell development, negative selection occurs in an attempt to ensure the antigen receptor:

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 39 of 57

A very high serum concentrations of one or more immunoglobulin classes, suggest all the following EXCEPT

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 40 of 57

Viral infections associated with neutropenia include

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 41 of 57

Which of the following isn't true about Allograft rejection

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 42 of 57

In the electrophoresis of human serum, which of the following is the most electronegative and thus migrates farthest toward the positive electrode?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 43 of 57

Involved in allergic responses

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 44 of 57

Increases vascular permeability

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 45 of 57

The X-linked lymphoproliferative (XLP) syndrome is classically associated with overwhelming infection with which organism?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 46 of 57

A patient presents with complaints of dark urine in the morning that clears up partially during the day. Lab work reveals hemolytic anemia, thrombosis in large vessels, and a deficiency in Hematopoiesis. Which of the following is the most likely?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 47 of 57

Phagocytic white cells (leukocytes, e.g. macrophages) congregate within when foreign organisms get through a cut in the skin.

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 48 of 57

Which of the following is NOT true when comparing innate to adaptive immunity?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 49 of 57

What type of cells produce type I interferons (IFN-Î± and IFN-Î²)?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 50 of 57

The deficiency of the complement proteins (C1q, C1q, C1s) or the complement receptors lead to the accumulation of immune complexes resulting in SLE or vasculitis .The deficiency affects the following complement pathway

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 51 of 57

Which of the following is true regarding immunoglobulin and T-cell receptor (TCR) proteins and gene segments?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 52 of 57

The TCR binds with , and the relatively surface of the TCR interacts with its ligand.

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 53 of 57

Which of the following is the cellular receptor for HIV attachments to T cells?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 54 of 57

Which of the following subunit vaccines is recommended for children but not adults?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 55 of 57

Which of the following is NOT involved in the antigen-antibody interaction?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 56 of 57

Edward jennar vaccinated against smallpox using...?

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ATI RN · Pediatric Immunizations NCLEX Questions

Question 57 of 57

Toll like receptors

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