Pediatric Immunization NCLEX Questions Ricci

ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 1 of 59

Which of the following is NOT true regarding the complement system?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 2 of 59

Genes involved in antigen processing

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 3 of 59

An epitope...?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 4 of 59

Cytokines

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 5 of 59

An infant presents with recurrent infections with Candida and viruses. Cardiac abnormalities result in the patient requiring heart surgery. During surgery, no thymus is found. Which of the following is the most likely?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 6 of 59

Uses integrin molecules to squeeze between endothelial cells

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 7 of 59

In the classical pathway, after the proteolysis of C3 complement pathway, which component is cleaved by C4bC2aC3b and initiate the formation of membrane attack complex

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 8 of 59

At what stage of B cell development are auto-reactive cells removed?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 9 of 59

Which of the following vaccines should not be administered to severely immunocompromised patients...?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 10 of 59

Multiple sclerosis

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 11 of 59

Killed vaccines are theoretically much safer than live vaccines, but cannot replicate in hosts and cannot enter intracellular antigen presenting pathways. Which of the following killed vaccines is recommended for children but not adults?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 12 of 59

A 5-month-old infant presented with reluctance to feed, lethargy, abdominal distension, and severe gingivitis. The parents are healthy relatives and give history of non-purulent omphalitis with separation of umbilical stump at the age of 2 months. His peripheral smear showed neutrophil count 24,000/mm3. Of the following, the MOST effective life saving measure is

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 13 of 59

A workup on an ill child revealed low levels of complement C3 in her blood. Which one of the following presentations did this child most likely manifest?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 14 of 59

Activation of the gene for IL-2, and eventually TH proliferation, is caused by a critical signal (along with TCR signal transduction) from ___ on the B cell and ___ on the T cell.

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 15 of 59

Antibody-dependent cellular cytotoxicity (ADCC) is the process by which natural killer cells destroy infected cells, identified by what immunoglobulin on the surface?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 16 of 59

Anaphylatoxins are chemotaxins that stimulate phagocytosis and degranulation. Which complement components is/are mainly involved?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 17 of 59

Which of the following doesn't Express MHC II

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 18 of 59

Monoclonal antibodies (mAb) are antibodies with a wide range of clinically important applications, such as pregnancy tests, cancer diagnosis, and cancer treatment. These antibodies are and come from parent cell(s).

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 19 of 59

Which of the following is an agent (e.g. aluminum salts, oil-based, virosomes) often used to modify or augment the effects of a vaccine by stimulating the immune system to respond to the vaccine more vigorously, and thus providing increased immunity to a particular disease?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 20 of 59

which of the following is not in LPS recognition pathway

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 21 of 59

What is the function of major histocompatibility complex (MHC) molecules?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 22 of 59

The treatment of choice for a 3-year-old boy with Wiskott-Aldrich syndrome is

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 23 of 59

A 4-month-old female presents with diarrhea and malabsorption, and on initial laboratory testing has a WBC count of 900/mmÃ‚Â³. Which of the following is the most likely diagnosis?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 24 of 59

Allelic exclusion is a process by which the protein from only one allele is expressed while other allele(s) are silenced. Allelic exclusion occurs (generally) in which of the following?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 25 of 59

Deletions in the T-cell CD154 (CD40L) gene produce?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 26 of 59

Antigen presenting cells (APCs) are required for T-cell recognition of specific antigen and activation. APCs accomplish this task by presenting antigen in the context of which of the following molecules?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 27 of 59

Immunoreceptor tyrosine-based activation motifs (ITAMs) are essential for signal transduction in cells.

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 28 of 59

Which of the following is NOT a major feature (characteristic) of the adaptive immune system?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 29 of 59

Medulla

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 30 of 59

All the following conditions can induce lymphopenia EXCEPT

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 31 of 59

Selective IgA deficiency is defined as serum IgA levels less than 10 mg/dL with normal levels of other immunoglobulins. The diagnosis cannot be confirmed until the patient is at least

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 32 of 59

generated in vesicles (extracellular infection, e.g. bacteria) bind to MHC molecules for presentation to T cells.

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 33 of 59

A 9-month-old boy presented with recurrent attacks of diarrhea, thrush, and failure to thrive shortly after birth. You suspect immune deficiency. Of the following, the MOST common cause of this condition is

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 34 of 59

CD4 in secondary lymphoid organs that has not been exposed to its antigen yet is called?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 35 of 59

A child is found to have a normal WBC count but serum concentrations of IgG, IgA, IgM, and IgE below the 95% lower limits for age. Which is the most likely diagnosis?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 36 of 59

Which of the following best activate NAÃ¯VE CD8 lymphocytes

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 37 of 59

Matching: Immunodeficiency - May be confused with AIDS

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 38 of 59

Where does a mature T cell encounter antigen for the first time?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 39 of 59

Which of the following is the correct order of lymphocyte extravasation?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 40 of 59

Phagocytic and cytotoxic activities; chemotactic factors

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 41 of 59

Chronic neutropenia may be induced by

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 42 of 59

In comparison toÎ±Î² T cells, Î´Î³ T cells and are hypothesized to be a line of immune defense.

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 43 of 59

What color light is emitted when antigens are exposed to UV light after being treated with fluorescein isothiocyte (FITC), such as in the test for Treponema pallidum (syphilis) or to dye the Chicago river for a particular holiday (fluorescein)?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 44 of 59

A child presents with a maculopapular rash on the extremities and trunk. Petechiae is found on the trunk and mucous membranes. Lab tests show a Neisseria infection and the physician is concerned about meningococcemia. Which of the following is the most likely?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 45 of 59

Neutropenia is noted in children in all of the following conditions EXCEPT

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Question 46 of 59

A 15-year-old boy presented with high fever, lymphadenopathy, hepatosplenomegaly, recurrent skin infections, silvery hair, and photophobia. Last year, he developed ataxia. The MOST characteristic finding in this condition is

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 47 of 59

Which of the following is the correct order of developmental stages for T cells?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 48 of 59

Which immune cell is responsible for the quickest release of histamine that causes the red itchy welts associated with allergies?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 49 of 59

Which of the following is NOT true regarding apoptosis of target cells?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 50 of 59

Which of the following binds to an Fc receptor on mast cells and basophils?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 51 of 59

19-year-old college student develops a rash. She works part-time in a pediatric AIDS clinic. Her blood is drawn and tested for specific antibody to the chicken pox virus (varicella-zoster). Which of the following antibody classes would you expect to find if she is immune to chicken pox?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 52 of 59

Because of a lack of genetic recombination in the MHC, blocks of alleles (haplotypes) are inherited together, and they are identical in families. Which of the following is the likely result of this?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 53 of 59

shock syndrome is mediated by cytokines secreted from cells.

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 54 of 59

Migrate and present antigen to T cells

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 55 of 59

Which of the following is NOT true regarding the mechanisms of generating antibody diversity?

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ATI RN · Pediatric Immunization NCLEX Questions Ricci

Question 56 of 59

Which of the following are cells with some lineage commitment and little or no selfrenewal capacity?

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Question 57 of 59

Activation of macrophages is best achieved by which cytokine?

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Question 58 of 59

Which of the following is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR), and is also known as a cytotoxic T cell (CTL)?

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Question 59 of 59

Each antibody molecule contains heavy chains and light chains.

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