ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 6 of 60
B cell co-receptor phosphorylation sites include Igα/Igβ and which of the following?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 7 of 60
Wrong about MHC molecules
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Question 8 of 60
Can transfer across the placental (maternal protection)
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 9 of 60
Which of the following is a function of the adaptive immune system and NOT the innate immune system?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 10 of 60
Mutations in TAP-1 or TAP-2 may alter the function of the heterodimer TAP. Which of the following is common for patients with TAP mutations?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 11 of 60
A 9-year-old boy with acute lymphoblastic leukemia on chemotherapy, presented with fever, aphthous stomatitis, and fatigue for the last 5 days. His absolute neutrophil count (ANC) was 450/μL and hemoglobin level was 10 gm/dl. The NEXT appropriate therapeutic measure is
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 12 of 60
Production of secreted antibodies (pAs site) involves a chain of amino acids with a stretch of charged (versus non charged) amino acids at the terminus, in comparison to membrane bound antibody production (pAm site).
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 13 of 60
Important role in allergic response; heparin & histamine
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 14 of 60
In addition to recurrent staphylococcal abscesses and elevated serum IgE, the clinical manifestations of hyperimmunoglobulinemia E (hyper-IgE) syndrome frequently include which of the following?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 15 of 60
the best sequence of inflammasome formation is
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 16 of 60
The activation of a naïve B cell, which generally requires a second accessory signal, occurs when the B cell exits the bloodstream and into a lymphoid organ, meets antigen, internalizes the BCR-antigen complex, and eventually becomes cells.
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 17 of 60
Which of the following is expressed by tumor cells to suppress T cells?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 18 of 60
An article published in the Oncoimmunology journal in September 2018. It is discussing an immunotherapy approach that relies on designing and infecting the cancer patient two viruses expressing Melanoma-associated antigen A3 (MAGE-A3). The two viruses, a replication-deficient type-5 human adenoviral (Ad-MAGEA3) and Maraba MGI rhabdovirus(MGI-MAGEA3), are studied in this article preclinically by infecting nonhuman primates(monkeys). This immunotherapy approach is considered:
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 19 of 60
Matching: Immunodeficiency - Elevated IgE levels and eosinophilia
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 20 of 60
Which of the following is a chemoattractant that attracts neutrophils to the site of infection?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 21 of 60
which of the following is wrong regarding Antimicrobial Peptides
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Question 22 of 60
Which of the following differentiates an antigen from an immunogen?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 23 of 60
This parasite (Onchcerca volvulus) lives outside its host's cells (extracellular); therefore, cytotoxic T cells (CTLs) are ineffective in clearing the organism. This inability on the part of CTLs is due to their requirement to engage which of the following surface structures for their cytotoxic activity?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 24 of 60
Which of the following TCR genetic chains contains V and J segments, similar to genes for immunoglobulin kappa and lambda light chains?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 25 of 60
Which of the following immune system components would NOT recognize a macromolecule epitope (binding site)?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 26 of 60
An infant presents with recurrent bacterial infections and partial albinism. Lab work reveals giant granules and neutropenia. Which of the following is the most likely?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 27 of 60
To reduce the number of bacterial infection in patients with chronic granulomatous disease (CGD), they should be given daily
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 28 of 60
A patient presents at age 6-months with pneumonia and difficulty fighting off infections of encapsulated bacteria and enteroviruses. A mutation in Bruton's tyrosine kinase (btk) is suspected. Which of the following is the most likely?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 29 of 60
A T cell located at the epithelial barrier of the gut is a
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 30 of 60
Tissue mast cells
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 31 of 60
Which of the following have not provided examples of secondary immunodeficiency?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 32 of 60
C5, C6, C7, and C8 deficiency usually lead to
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 33 of 60
An 8-year-old child having coarse facial features seen by dentist because of failure to shed primary teeth and visited an orthopedician due to frequent fractures of lower limbs, now presented with skin abscesses and eczema. Of the following, the MOST likely diagnosis is
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Question 34 of 60
A 45-year-old female presents with anorexia and some abdominal pain. Fecal smears reveal the presence of Taenia eggs, products of a parasitic tapeworm infection. Which one of the following cells would be most effective in defense against this parasite?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 35 of 60
Ankylosing spondylitis
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 36 of 60
which of the following is needed to ensure a healthy T cell army that doesn't attack our own cells?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 37 of 60
Which of the following has an immunoglobulin fold?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 38 of 60
Which of the following isotypes of antibodies activate the complement cascade if bound to antigen?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 39 of 60
A 3-year-old girl presented with recurrent attacks of chest infection and frequent episodes of chronic diarrhea, stool examination revealed Giardia lamblia and serum IgA level was very low. Regarding this condition, all the following are true EXCEPT
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 40 of 60
In the lectin complement pathway, mannan-binding lectin (MBL) indirectly activates which of the following components?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 41 of 60
Allows for flexibility
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 42 of 60
Which of the following is NOT true regarding live viral vectored vaccines?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 43 of 60
Forms a pore in the target cell membrane (like MAC)
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 44 of 60
A person develops a viral infection and both T and B cells become activated to fight the infection. In which way is antigen recognition by B cells different from antigen recognition by T cells?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 45 of 60
Which of the following is used to enumerate and/or separate live cells that express an antigen, sorted by applying an electric charge to the stained cells?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 46 of 60
At what stage does selection occur and where in the thymus does it occur?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 47 of 60
a person developed an extracellular bacterial infection With the subsequent release of IGM, what is the most What is the most important function of IGM in this infection
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 48 of 60
You inject a mouse with an antigen that it has never been exposed to it before, the injection takes place at week 0 , at week 4 you inject the same mouse with the same foreign antigen, choose the right statement
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 49 of 60
Which of the following is only contained in heavy chains and not in light chains?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 50 of 60
MHC class I has three genes (HLA-A, HLA-B, & HLA-C). Which of the following is the correct order from most alleles (most polymorphic) to least alleles?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 51 of 60
Antibodies in our body are produced by:
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 52 of 60
Recognition of antigen
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 54 of 60
During B cell development, when is there rearrangement in the heavy (H) chain of the immunoblobulin gene started?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 55 of 60
Which of the following components of the innate immune system involves cytokines produced by macrophages, which are produced during infection?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 56 of 60
In contrast toαβ T cells, γδ T cells recognize certain peptide and nonpeptide antigens ___ processing and in the ___ of MHC class I and/or II molecules.
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 57 of 60
Which of the following molecules is necessary (not accessory) for antigen recognition and T cell activation?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 58 of 60
Regarding mucosa-associated lymphoid tissue (MALT), which of the following is secreted by B cells across the epithelium?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 59 of 60
A deficiency in complement inhibitors could lead to which of the following?
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ATI RN · Pediatric Immunization NCLEX Questions Quizlet
Question 60 of 60
In the adult, the primary lymphoid organs, whose cells expand clonally, are the and secondary lymphoid organs, which create effector cells, are the , as well as mucosa associated lymphoid tissue (MALT) lining the respiratory, GI, and reproductive tracts.
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