Which of the following locations has cell that transport the antigens by transcytosis into sub-epithelial tissues (e.g. lamina propria) where they encounter lymphocytes?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 2 of 59
If alternative processing uses the second polyadenylation site, then what type of heavy chain mRNA is derived?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 3 of 59
Matching: Immunodeficiency - Lymphopenia plus severe neutropenia
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 4 of 59
The classical and alternative pathways meet at complement component:
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 5 of 59
Which of the following is NOT true regarding interferon?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 6 of 59
Directly: some recognize nonpeptide phosphorylated lipids and carbohydrates; other recognize antigen that have not been processed
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 7 of 59
Degrade host cell proteins, activate caspase enzyme system
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 8 of 59
All of the following are actions of IL-1 EXCEPT
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 9 of 59
Matching: Complement deficiency - Fatal meningococcal infection in males
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 10 of 59
A 15-year-old boy with rheumatoid arthritis, on quinine for 6 months, presented with fever, aphthous stomatitis, and fatigue for the last 5 days. His absolute neutrophil count (ANC) was 700/μL. The MOST next appropriate therapeutic measure to be done when quinine withdrawal fails to improve neutropenia is
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 11 of 59
Macrophages recognize microorganisms through the Interaction of their substances with what receptor?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 12 of 59
Eventual elimination of antigen
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 13 of 59
Has different subtypes
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 14 of 59
The aim of monoclonal antibody production is to produce cells that only secrete immunoglobulin directed against the antigen used in immunization. Which of the following hybridoma production steps is NOT correct?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 15 of 59
Which of the following statements is TRUE regarding diurnal variation of the absolute eosinophil count (AEC)?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 16 of 59
which of the following is a Pathogen associated molecular pattern
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 17 of 59
Which one of the following sets of cells can present antigen to helper T cells?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 18 of 59
A patient encounters the helminth Onchcerca volvulus after swimming in a parasite-infested river in West Africa. Following interaction with the patient's innate immune system, one would expect and hope for the development of which subtype of T cells in response to the organism?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 19 of 59
A 6-month-old presents with recurrent cellulitis and bacteremias due to Staphylococcus aureus. The white blood cell count is 2500 with 5% neutrophils, 10% eosinophils, 35% monocytes, and 50% lymphocytes. The platelet count is 650,000. A brother and a female cousin died at the age of 18 months and 2 years, respectively. The most likely diagnosis is
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 20 of 59
Which of the following TCR genetic chains contain D-segments, similar to immunoglobulin heavy chains?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 21 of 59
A CD3pos cell that secretes perforin and granzyme is a:
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 22 of 59
Which of the following components of the innate immune system involves recognition molecules such as mannan-binding lectin (MBL) for bacteria with mannose on the surface?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 23 of 59
Enhance diapedesis and stimulate TH2 responses
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 24 of 59
which of the following cells will be the last cell to perform its function in skin pathogen invasion
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 25 of 59
A 4.5-year-old boy presented with history of recurrent attack of secretary otitis media and purulent nasal discharge, Haemophilus influenza revealed by culture of ear discharge, on physical examination there is no tonsillar tissue and no palpable lymph nodes. Of the following, the MOST appropriate test to confirm the diagnosis is
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 26 of 59
Which one of the following leukocytes is considered a 'granulocyte'?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 27 of 59
Which of the following best describes complementary system
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 28 of 59
T cell activation of TH1 leads to ___ antibody production and opsonization (or macrophage activation). Activation of TH2 leads to ___ antibody production and activation of mast cells and eosinophils.
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 29 of 59
Immunostimulatory complexes (ISCOMS) can be used for mucosal vaccines and induce widespread mucosal immunity in the gut and respiratory tract. They are the one way that response can be promoted.
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 30 of 59
The diagnosis of chronic granulomatous disease CGD is MOST often made by
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 31 of 59
Light microscopy of neutrophils for the presence of giant granules can help to diagnose
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 32 of 59
A 66-year-old man with advanced pancreatic cancer develops cachexia (loss of mass) Which cytokine is primarily responsible for the cachexia seen in certain patients with cancer or debilitating infections?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 33 of 59
Which of the following has the surface marker CD34 instead of the surface marker CD19, during B cell development?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 34 of 59
Evidence is accumulating showing that polymorphism in the MHC may be advantageous. Homozygosity at HLA class I has been shown to be a(n) with respect to HIV/AIDS. Similarly, there is evidence that homozygosity at HLA class II the risk of hepatitis B virus infection persisting.
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 35 of 59
The transporter associated with antigen presentation (TAP) the peptides to traverse the membrane bilayer of the endoplasmic reticulum and bind in the empty peptide-binding groove of nascent MHC molecules being synthesized in the endoplasmic reticulum.
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 36 of 59
Penicillin can form a hapten-carrier conjugate with a self-protein that can then act as an immunogen and generate an immunoglobulin antibody, and can cross-react with a number of other antibiotics. This can complicate the treatment of bacterial infections in these patients because they are unable to take the antibiotics necessary to combat the infection.
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 37 of 59
Where are double-positive (DP) cells found?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 38 of 59
Anaphylaxis can be triggered by cross-linking of IgE receptors on...?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 39 of 59
Each polypeptide chain (heavy and light) on immunoglobulin has a variable (V) and constant (C) region. Immunoglobulin chains are encoded by that is/are rearranged during development to assemble a functional gene encoding either a heavy or a light chain.
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 40 of 59
Phagocytose, bacteriocidal activity, ADCC
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 41 of 59
Fab Fragment?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 42 of 59
The normal immunological control of tumors is referred to as?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 43 of 59
Macrophages
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 44 of 59
A TCR complex is comprised of the TCR, CD3 molecules, and which of the following CD3 chains?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 45 of 59
To prevent inadvertent complement activation, eight inhibitors exist. Which of the following is an inhibitor preventing activation of C2 and C4, and prevents C3 activation by the alternative pathway?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 46 of 59
In the embryonic human, the primary lymphoid organs are initially in the yolk sac, then in the fetal , and finally in the
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 47 of 59
A patient presents in the winter months with swollen lips. The patient says they forgot their lip balm. Uncontrolled activation of the classical complement pathway is responsible for the swelling. Records show the patient has a C1 inh deficiency. Which of the following does this patient have?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 48 of 59
A cluster of genes that encode proteins
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 49 of 59
Class III MHC genes encode for which of the following?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 50 of 59
Which of the following is a messenger that mediates the connection between the innate and adaptive immune systems?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 51 of 59
Protein antigens bound to complement component C3d can bind simultaneously to both and the BCR. This enables the co-receptor complex to cluster and crosslink with the BCR, inducing phosphorylation.
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 52 of 59
Tolerance refers to the ability of B cells to:
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 53 of 59
Which of the following peripheral immune tissues is likely to be different from teen through life to old age?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 54 of 59
Which of the following is not a prominent feature of Wiskott-Aldrich syndrome?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 55 of 59
A 15-month-old male child presented with thrombocytopenic purpura, atopic dermatitis, and recurrent infections caused by cytomegalovirus and P.jiroveci. Immunoglobulin assay revealed elevated IgE and IgA with decreased IgM levels. Of the following, the MOST likely diagnosis is
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 56 of 59
What is the primary response seen in acute-phase responses to infection?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 57 of 59
Given that an individual's parents have completely different HLA genes, that individual will have about different class I and II MHC molecules on the surface of certain of their lymphoid cells.
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 58 of 59
The γδ T cell acts as a part of the first line of defense, recognizing microbial invaders. They appear to recognize commonly occurring microbial pathogens. Where can γδ T cells be found?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
ATI RN · Pediatric Immunization NCLEX Questions
Question 59 of 59
A patient is being seen for recurrent infections. However, the patient does not seem to think anything special of these infections and there has been no previous diagnosis other than the infections. Lab work reveals abnormalities with hypochlorous acid and H2O2 conversion. Which of the following is the most likely?
Select an option. Use Strike to cross one out.
Rationale
Did you know the question?
End of free preview
You have finished the first five questions. Sign in to continue this set and save your progress.
