Hematogenous dissemination of HSV to the central nervous system occur in
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Question 2 of 90
Which of the following features labels a patient with acute lymphoblastic leukemia as a low risk patient?
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Question 3 of 90
The palmar grasp is gone by 4 months of age and present by gestational age of
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Question 4 of 90
Massive pulmonary embolism causes
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Question 5 of 90
WAGR syndrome implies the following
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Question 6 of 90
Rb gene analysis is useful in the workup of
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Question 7 of 90
A 10-year-old female with history of insidious onset of fatigue, malaise, and progressive muscle weakness, accompanied by low-grade fevers and scaly, red plaques are found across the knuckles, she is not able to sit up from a supine position, investigations revealed: elevated muscle enzymes (ALT, AST, LDH, CPK, and aldolase), EMG abnormalities: fasciculations, needle insertion irritability, and high-frequency discharges. Of the following, the MOST serious complication that can occurs in this patient is the development of
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Question 8 of 90
Which is not true concerning HIV infection?
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Question 9 of 90
Gilbert disease, caused by a mutation of the promoter region of glucuronosyl transferase, is characterized by development of
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Question 10 of 90
Vaccines are defined as whole or parts of microorganisms administered to prevent an infectious disease. Which of the following is a live attenuated vaccine?
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Question 11 of 90
A 7-day-old infant, a product of normal vaginal delivery, presented with history of clear, watery discharge from both eyes that became purulent; on examination there is conjunctival hyperemia and chemosis. Of the following, the recommended treatment is
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Question 12 of 90
Febrile children with sickle cell anemia are at an increased risk for having overwhelming sepsis. Some of these children can be given intramuscular ceftriaxone and treated as outpatients. Which of the following should lead to hospitalization?
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Question 13 of 90
A 16-month-old infant present with high fever, cough, coryza, and conjunctivitis; after 3 days a macular rash begins on the head and spreads over most of the body. On examination; cervical lymphadenopathy, splenomegaly, and temperature 40°C. CBC reveals WBC count 3000/mm³ The severity of this illness is MOST likely related to the extent of
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Question 14 of 90
Production of an exopolysaccharide protective biofilm (slime) is an attribute of which organism?
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Question 15 of 90
The MOST common complication of acute severe meningococcal septicemia is
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Question 16 of 90
Which of the following vaccines is contraindicated for a patient with X-linked agammaglobulinemia?
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Question 17 of 90
In neonatal hyperbilirubinemia, bilirubin is produced by the catabolism of hemoglobin in the reticuloendothelial system, one gram of hemoglobin produces
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Question 18 of 90
Three mechanisms can produce fever: pyrogens, heat production exceeding loss, and defective heat loss. Endogenous pyrogens include
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Question 19 of 90
In late-onset sepsis (8 to 28 days), the LEAST common focal infection result from hematogenous seeding is
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Question 20 of 90
Twin-to-twin transfusion syndrome suggested by
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Question 21 of 90
Echocardiography should be performed in critically ill infants with pertussis to detect presence of
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Question 22 of 90
All the following are major recommended indications for IVIG EXCEPT
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Question 23 of 90
One of the following statements regarding tinidazole is TRUE
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Question 24 of 90
In intraventricular hemorrhage (IVH), posthemorrhagic hydrocephalus may be managed with serial daily lumbar punctures, an external ventriculostomy tube, or a permanent ventricular-peritoneal shunt. Implementation of the shunt often is delayed because of the
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Question 25 of 90
A 5-year- old boy presented with abdominal mass, hematuria and hypertension. Of the following, the MOST likely diagnosis is
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Question 26 of 90
All the following are tools for assessment of central nervous system perfusion EXCEPT
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Question 27 of 90
Antimotility agents have a role in therapy of acute diarrhea in infants and toddlers with gastroenteritis due to
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Question 28 of 90
Hemorrhagic cystitis is a complication of which of the following chemotherapeutic agents?
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Question 29 of 90
Which is not associated with papillomaviruses?
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Question 30 of 90
During intrauterine life, hemoglobin concentration increases from 8 to 10 g/dL at 12 weeks to 16.5 to 18 g/dL at
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Question 31 of 90
Regarding herpes simplex virus (HSV) infection, all the following statements are true EXCEPT
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Question 32 of 90
Modified Duke clinical criteria for diagnosis of infective endocarditis are two major criteria or one major and three minor criteria or five minor criteria. Of the following, a major criteria is
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Question 33 of 90
The MOST common site for Ewing sarcoma is
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Question 34 of 90
Polycythemia is an excessively high hematocrit, which may lead to blood hyperviscosity; it is defined as central hematocrit of
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Question 35 of 90
A 5-year-old urban male was admitted to the hospital because of low-grade fever, flaccid paralysis of both legs, sensory changes, and absent ankle deep tendon reflexes. The child had received only two immunizations with OPV at the age of 2 and 6 months. His diagnosis is most probably
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Question 36 of 90
An 11-year-old adolescent girl presents with a complaint of odorless/colorless vaginal discharge. Locally you find a well estrogenized vulva and hymen without erythema or excoriation. Of the following, the MOST appropriate action is to
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Question 37 of 90
CNS involvement should be excluded at the time of diagnosis of acute lymphoblastic leukemia by
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Question 38 of 90
Steroid could be of MINIMAL help in which of the following oncologic event?
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Question 39 of 90
Severe cold injury in an infant is manifested by all the following EXCEPT
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Question 40 of 90
Necrotizing enterocolitis (NEC) occurs in 1 to 3 per 1000 live births but the incidence of NEC in neonates admitted to the neonatal intensive care unit is
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Question 41 of 90
All the following are true about varicella in unvaccinated individuals EXCEPT
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Question 42 of 90
Which organ is rarely involved by metastatic neuroblastoma?
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Question 43 of 90
A 5th year medical student is asking you about the main difference between defibrillation and cardioversion. Of the following, the BEST answer is
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Question 44 of 90
Manifestations of Chlamydia trachomatis pneumonia include all of the following EXCEPT
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Question 45 of 90
The MOST prevalent hepatitis virus infection in HIV-infected persons is
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Question 46 of 90
Diagnosis of chancroid in infants and children is a strong evidence of sexual abuse. Chancroid is caused by
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Question 47 of 90
The MOSTLY involved joint in suppurative arthritis is
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Question 48 of 90
A 2-year-old child presented with recurrent attacks of stridor and harsh cough, sudden in onset mainly at night with no fever; most of the time the stridor relieved during the trip to hospital. Of the following, the MOST likely diagnosis is
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Question 49 of 90
Which is not true of herpes simplex virus (HSV) infections in neonates?
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Question 50 of 90
Patients who should receive prophylaxis for $P$. carinii pneumonia are those afflicted with
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Question 51 of 90
The drug that is recommended as initial therapy for nondisseminated gonococcal disease in children and adults is
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Question 52 of 90
Human herpesvirus 6 (HHV-6A and HHV-6B) and human herpesvirus 7 (HHV-7) cause infection in infancy and early childhood. HHV-6B is responsible for the majority of cases of roseola infantum (exanthema subitum or sixth disease). All the following are true EXCEPT
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Question 53 of 90
Hemorrhagic disease of the newborn (HDN) is prevented by administration of single dose of vitamin K (1 mg)
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Question 54 of 90
Diphtheria and tetanus toxoids and acellular pertussis vaccine (DTaP) should be administered at which ages?
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Question 55 of 90
Diphtheria is an acute toxic infection; toxic cardiomyopathy occurs in 10-25% of patients with respiratory diphtheria and is responsible for 50-60% of deaths. Of the following, the mainstay of therapy is
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Question 56 of 90
Colitis with minimal fecal leukocytes occur in infection with
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Question 57 of 90
Charcoal that is used for gastric decontamination in case of acute poisoning is effective against
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Question 58 of 90
Human brucellosis is caused by organisms of the genus Brucella and continues to be a major public health problem worldwide. All the following are true EXCEPT
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Question 59 of 90
Seizure in cholera is commonly due to
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Question 60 of 90
Completion of the Tanner stages in females should take 4 to 5 years. The peak growth spurt usually occurs during
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Question 61 of 90
A 5-year-old child (who had neurosurgical procedure before 1 month) presented with fever, headache, repeated vomiting, and nuchal rigidity; Kemig and Brudzinski are positive; cerebrospinal fluid findings are (leukocytes 550/μL with PMNs predominate), protein (120 mg/dL), and glucose (44 mg/dL); serum glucose (118 mg/dL). Of the following, the MOST common organism that cause this condition is
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Question 62 of 90
Monthly injections of palivizumab, a RSV-specific monoclonal antibody, initiated just before the onset of the RSV season confers some protection from severe RSV disease. Palivizumab is indicated for some infants under 2 years old with all the following EXCEPT
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Question 63 of 90
A 4-year-old child presents with acute onset of colicky abdominal pain, blood-stained diarrhea, and tenesmus. There is no fever. Trophozoites are seen in the stool. The family has recently returned from a trip to Mexico. Which etiology should be suspected?
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Question 64 of 90
Of the following, the MOST common viral cause of common cold is
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Question 65 of 90
The preferred treatment of Lyme disease in a child 13 years of age is
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Question 66 of 90
Kawasaki disease closely resembles toxic shock syndrome clinically. However, many of the clinical features of toxic shock syndrome are usually absent or rare in Kawasaki disease like
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Question 67 of 90
Cephalexin is a cephalosporin active against S. aureus, Streptococcus, E. coli, Klebsiella, and Proteus. To which generation of cephalosporins it belongs?
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Question 68 of 90
Ebstein anomaly can be induced by teratogenic effect of
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Question 69 of 90
All the following are causes of very high temperatures (>41°C) EXCEPT
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Question 70 of 90
All the following statements regarding ABO incompatibility are true EXCEPT
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Question 71 of 90
A 6-year- old girl presented with a 3-month history of cervical swelling, fever, and excessive sweating. In the context of suspecting Hodgkin lymphoma. Of the following, the BEST diagnostic procedure at this time is
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Question 72 of 90
Arterial blood gas analysis (BGA) should perform in all infants with significant respiratory distress, whether or not cyanosis is perceived. All the following are true about a normal values of arterial BGA in term infants EXCEPT
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Question 73 of 90
Which of the following routes of transmission has been associated with several large outbreaks of human listeriosis?
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Question 74 of 90
The diagnosis of UTI in infants requires the presence of both pyuria and single pathogenic organism of at least
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Question 75 of 90
The MOST common complication of measles is
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Question 76 of 90
A child wearing helmet during riding bicycle is an example of which strategy in trauma prevention in childhood?
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Question 77 of 90
The MOST important therapy for primary pulmonary hypertension of the newborn (PPHN) is
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Question 78 of 90
A 7-year-old child presented with persistent mucopurulent rhinorrhea, nasal stuffiness, headache and cough, mainly at night preceded by history flue like illness; on examination there are facial swelling and tenderness. Of the following, the major predisposing factor for the development of this condition is
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Question 79 of 90
Morning stiffness is seen in which of the following pediatric diseases?
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Question 80 of 90
Which of the following classes of chemotherapeutics carries a particular risk for the development of future leukemia?
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Question 81 of 90
Criteria for diagnosis of Kawasaki disease include all the following EXCEPT
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Question 82 of 90
Of the long-term adverse effects of brain tumor therapy, the one that carries particular significance to infants is
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Question 83 of 90
Which describes the recommended use of HRIG for postexposure rabies prophylaxis in the United States?
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Question 84 of 90
Infants with congenital rubella should be isolated while in the hospital and kept away from susceptible pregnant women when sent home for about
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Question 85 of 90
The peak age group of HHV-6 infection is
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Question 86 of 90
A 13-month-old previously healthy child presents on New Year's Eve with a 1-day history of fever, lethargy, and left-side focal motor seizure activity. The cerebrospinal fluid (CSF) reveals 170 lymphocytes $/ \mathrm{mm}^3, 400$ red blood cells $/ \mathrm{mm}^3$, protein of $150 \mathrm{mg} / \mathrm{dL}$, and normal glucose level. MRI scan reveals right temporal abnormalities. The single most appropriate therapy to begin empirically while awaiting definitive diagnosis would be
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Question 87 of 90
The leading protozoal cause of diarrhea in children worldwide is
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Question 88 of 90
A 9-month-old infant have remittent fever for the last 4 days with nasal congestion and mild cough, today he developed maculopapular rash after subsidence of the fever. Of the following, the MOST likely diagnosis is
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Question 89 of 90
Acute rheumatic carditis usually presents as cardiac murmurs and
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Question 90 of 90
A mother of an 11-month-old baby girl who had ingested a tasteless alkali, initial endoscopy revealed full-thickness liquefaction necrosis of the esophagus. She underwent successful dilatation of esophageal stricture after 3 weeks from the accident. Mother is asking about any other future risk of this condition. Of the following, the MOST appropriate explanation include
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